[HTML][HTML] Broken but not beaten: Challenge of reducing the amyloids pathogenicity by degradation
MI Sulatsky, OV Stepanenko, OV Stepanenko… - Journal of Advanced …, 2024 - Elsevier
Background The accumulation of ordered protein aggregates, amyloid fibrils, accompanies
various neurodegenerative diseases (such as Parkinson's, Huntington's, Alzheimer's, etc.) …
various neurodegenerative diseases (such as Parkinson's, Huntington's, Alzheimer's, etc.) …
Understanding anomalous mobility of proteins on SDS‐PAGE with special reference to the highly acidic extracellular domains of human E‐and N‐cadherins
During SDS‐PAGE experiments, proteins generally display electrophoretic mobility in
kee** with their molecular weights; however, some proteins display anomalies in mobility …
kee** with their molecular weights; however, some proteins display anomalies in mobility …
[HTML][HTML] Effect of divalent cations on bovine serum albumin (BSA) and tannic acid interaction and its influence on turbidity and in vitro protein digestibility
Tannins, proteins, and divalent cations interactions are important for many processes in the
food industry and human and animal nutrition and health. The effect of magnesium, calcium …
food industry and human and animal nutrition and health. The effect of magnesium, calcium …
Multiple thermostable enzyme hydrolases on magnetic nanoparticles: An immobilized enzyme-mediated approach to saccharification through simultaneous xylanase …
Microbe-derived enzymes such as xylanases, cellulases and amylases, are efficient at
hydrolyzing plant biomass. Efforts to harness the functionalities of these enzymes towards …
hydrolyzing plant biomass. Efforts to harness the functionalities of these enzymes towards …
Role of salts and solvents on the defibrillation of food dye “sunset yellow” induced hen egg white lysozyme amyloid fibrils
Several food dyes are known to induce amyloid fibrillation when interacting with proteins.
Here, we studied the role of sunset yellow (SY) in the amyloid fibrillation of hen egg white …
Here, we studied the role of sunset yellow (SY) in the amyloid fibrillation of hen egg white …
Negatively charged food additive dye “Allura Red” rapidly induces SDS-soluble amyloid fibril in beta-lactoglobulin protein
NA Al-Shabib, JM Khan, A Malik, AM Alsenaidy… - International journal of …, 2018 - Elsevier
Recent studies have led to an increased interest to categorize small molecular inhibitors of
protein fibrillation. In this study, we used spectroscopy, microscopy and gel electrophoresis …
protein fibrillation. In this study, we used spectroscopy, microscopy and gel electrophoresis …
Unveiling the stimulatory effects of tartrazine on human and bovine serum albumin fibrillogenesis: Spectroscopic and microscopic study
NA Al-Shabib, JM Khan, MA Alsenaidy… - Spectrochimica acta part …, 2018 - Elsevier
Amyloid fibrils are playing key role in the pathogenesis of various neurodegenerative
diseases. Generally anionic molecules are known to induce amyloid fibril in several …
diseases. Generally anionic molecules are known to induce amyloid fibril in several …
Denaturant effect on amyloid fibrils: Declasterization, depolymerization, denaturation and reassembly
MI Sulatsky, AI Sulatskaya, OV Stepanenko… - International journal of …, 2020 - Elsevier
Accumulation of amyloid fibrils in organism accompanies many serious diseases, such as
Alzheimer's and Parkinson's diseases, diabetes, prion diseases, etc. It is generally accepted …
Alzheimer's and Parkinson's diseases, diabetes, prion diseases, etc. It is generally accepted …
SDS-induced hexameric oligomerization of myotoxin-II from Bothrops asper assessed by sedimentation velocity and nuclear magnetic resonance
We report the solution behavior, oligomerization state, and structural details of myotoxin-II
purified from the venom of Bothrops asper in the presence and absence of sodium dodecyl …
purified from the venom of Bothrops asper in the presence and absence of sodium dodecyl …
Multispectroscopic and computational insights into amyloid fibril formation of alpha lactalbumin induced by sodium hexametaphosphate
The impact of sodium hexametaphosphate (SHMP) on the aggregation behavior of α-
lactalbumin (α-LA) was studied at pH 7.4 and 2.0. Turbidity measurements showed a …
lactalbumin (α-LA) was studied at pH 7.4 and 2.0. Turbidity measurements showed a …