Myocardial mesostructure and mesofunction

AJ Wilson, GB Sands, IJ LeGrice… - American Journal of …, 2022 - journals.physiology.org
The complex and highly organized structural arrangement of some five billion
cardiomyocytes directs the coordinated electrical activity and mechanical contraction of the …

In utero diffusion MRI: challenges, advances, and applications

D Christiaens, PJ Slator… - Topics in Magnetic …, 2019 - journals.lww.com
In utero diffusion magnetic resonance imaging (MRI) provides unique opportunities to
noninvasively study the microstructure of tissue during fetal development. A wide range of …

Insights into the passive mechanical behavior of left ventricular myocardium using a robust constitutive model based on full 3d kinematics

DS Li, R Avazmohammadi, SS Merchant… - Journal of the …, 2020 - Elsevier
Myocardium possesses a hierarchical structure that results in complex three-dimensional
(3D) mechanical behavior, forming a critical component of ventricular function in health and …

Development of helical myofiber tracts in the human fetal heart: analysis of myocardial fiber formation in the left ventricle from the late human embryonic period using …

S Nishitani, N Torii, H Imai, R Haraguchi… - Journal of the …, 2020 - ahajournals.org
Background Detection of the fiber orientation pattern of the myocardium using diffusion
tensor magnetic resonance imaging lags≈ 12 weeks of gestational age (WGA) behind fetal …

[HTML][HTML] Adaptation of Left Ventricular Function and Myocardial Microstructure in Fetuses with Right Ventricular Hypoplasia

J Ma, Y Li, H Cao, Y Yuan, S Chen, L Hong… - Canadian Journal of …, 2024 - Elsevier
Background This study aimed to evaluate changes in left ventricular (LV) function and
myocardial microstructure in fetuses with right ventricular hypoplasia (RVH) using two …

[HTML][HTML] Evaluation of right ventricular function and myocardial microstructure in fetal hypoplastic left heart syndrome

J Ma, Y Yuan, L Zhang, S Chen, H Cao, L Hong… - Journal of Clinical …, 2022 - mdpi.com
Right ventricular (RV) function is one of the critical factors affecting the prognosis of fetuses
with hypoplastic left heart syndrome (HLHS). Our study objectives included assessment of …

Former-preterm lambs have persistent alveolar simplification at 2 and 5 months corrected postnatal age

MJ Dahl, S Bowen, T Aoki… - … of Physiology-Lung …, 2018 - journals.physiology.org
Preterm birth and mechanical ventilation (MV) frequently lead to bronchopulmonary
dysplasia, the histopathological hallmark of which is alveolar simplification. How …

Toward cardiac tissue characterization using machine learning and light-scattering spectroscopy

NJ Knighton, BK Cottle, S Tiwari… - Journal of …, 2021 - spiedigitallibrary.org
Significance: The non-destructive characterization of cardiac tissue composition provides
essential information for both planning and evaluating the effectiveness of surgical …

Microarchitecture of the hearts in term and former‐preterm lambs using diffusion tensor imaging

B Le, P Ferreira, S Merchant, G Zheng… - The Anatomical …, 2021 - Wiley Online Library
Diffusion tensor imaging (DTI) is an MRI technique that can be used to map cardiomyocyte
tracts and estimate local cardiomyocyte and sheetlet orientation within the heart. DTI …

Detailed quantification of cardiac ventricular myocardial architecture in the embryonic and fetal mouse heart by application of structure tensor analysis to high …

P Garcia-Canadilla, TJ Mohun, B Bijnens… - Frontiers in Cell and …, 2022 - frontiersin.org
The mammalian heart, which is one of the first organs to form and function during
embryogenesis, develops from a simple tube into a complex organ able to efficiently pump …