During the past decades, better understanding of relapsing-remitting multiple sclerosis
disease mechanisms have led to the development of several disease-modifying therapies …

Diffusion tensor imaging (DTI) is an effective means of quantifying parameters of
demyelination and axonal loss. The application of DTI in Multiple Sclerosis (MS) has yielded …

Abstract Background and Purpose Multiple sclerosis (MS) is an unpredictable disease
characterised by a highly variable disease onset and clinical course. Three main clinical …

Multiple sclerosis leads to diffuse damage of the central nervous system, affecting also the
normal-appearing white matter. Demyelination and axonal degeneration reduce regional …

Brain imaging is increasingly used to support clinicians in diagnosing multiple sclerosis
(MS) and monitoring its progression. However, the role of magnetic resonance imaging …

Neurodegenerative disorders leading to dementia are common diseases that affect many
older and some young adults. Neuroimaging methods are important tools for assessing and …

Diffusion tensor imaging (DTI) is sensitive to white matter (WM) damage in multiple sclerosis
(MS), not only in focal lesions but also in the normal-appearing WM (NAWM). However, DTI …

In a multicenter setting, we applied voxel‐based methods to different structural MR imaging
modalities to define the relative contributions of focal lesions, normal‐appearing white …

Importance Although magnetic resonance imaging (MRI) is useful for monitoring disease
dissemination in space and over time and excluding multiple sclerosis (MS) mimics, there …

Purpose To investigate the ability of diffusion-tensor imaging (DTI) and T2 to help detect the
mildest nerve lesion conceivable, that is, subclinical ulnar neuropathy at the elbow …