Abstract Galaxy (homepage: https://galaxyproject. org, main public server: https://usegalaxy.
org) is a web-based scientific analysis platform used by tens of thousands of scientists …

Data sharing, integration and annotation are essential to ensure the reproducibility of the
analysis and interpretation of the experimental findings. Often these activities are perceived …

UCSC Xena is a visual exploration resource for both public and private omics data,
supported through the web-based Xena Browser and multiple turn-key Xena Hubs. This …

Abstract PLAZA (https://bioinformatics. psb. ugent. be/plaza) is a plant-oriented online
resource for comparative, evolutionary and functional genomics. The PLAZA platform …

Mitochondrial DNA (mtDNA) profiles can be classified into phylogenetic clusters
(haplogroups), which is of great relevance for evolutionary, forensic and medical genetics …

Abstract Since 2009 the EMBL-EBI Job Dispatcher framework has provided free access to a
range of mainstream sequence analysis applications. These include sequence similarity …

PredictProtein is a meta-service for sequence analysis that has been predicting structural
and functional features of proteins since 1992. Queried with a protein sequence it returns …

Functional enrichment analysis is a key step in interpreting gene lists discovered in diverse
high-throughput experiments. g: Profiler studies flat and ranked gene lists and finds …

Horizontal transfer, gene loss, and duplication result in dynamic bacterial genomes shaped
by a complex mixture of different modes of evolution. Closely related strains can differ in the …

Comparing newly obtained and previously known nucleotide and amino-acid sequences
underpins modern biological research. BLAST is a well-established tool for such …