Needle biopsy adequacy in the era of precision medicine and value-based health care

KPH Pritzker, HJ Nieminen - Archives of pathology & …, 2019 - meridian.allenpress.com
Context.—Needle biopsy of diseased tissue is an essential diagnostic tool that is becoming
even more important as precision medicine develops. However, the capability of this …

Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis

F Penkava, MDC Velasco-Herrera, MD Young… - Nature …, 2020 - nature.com
Psoriatic arthritis (PsA) is a debilitating immune-mediated inflammatory arthritis of unknown
pathogenesis commonly affecting patients with skin psoriasis. Here we use complementary …

Synovial biopsies for molecular definition of rheumatoid arthritis and treatment response phenoty**: where can we improve?

FS Iaquinta, F Rivellese, C Pitzalis - Expert Review of Molecular …, 2023 - Taylor & Francis
Introduction The extensive knowledge gained in the cellular and molecular mechanisms
underlying Rheumatoid Arthritis (RA) pathogenesis has led to therapeutic advances …

B cell synovitis and clinical phenotypes in rheumatoid arthritis: relationship to disease stages and drug exposure

F Rivellese, F Humby, S Bugatti… - Arthritis & …, 2020 - Wiley Online Library
Objective To define the relationship of synovial B cells to clinical phenotypes at different
stages of disease evolution and drug exposure in rheumatoid arthritis (RA). Methods …

[HTML][HTML] The EFSUMB guidelines and recommendations for musculoskeletal ultrasound–part II: joint pathologies, pediatric applications, and guided procedures

E Naredo, SC Rodriguez-Garcia… - Ultraschall in der …, 2022 - thieme-connect.com
The second part of the Guidelines and Recommendations for Musculoskeletal Ultrasound
(MSUS), produced under the auspices of EFSUMB, following the same methodology as for …

EULAR points to consider for minimal reporting requirements in synovial tissue research in rheumatology

A Najm, F Costantino, S Alivernini, A Alunno… - Annals of the …, 2022 - ard.bmj.com
Background Synovial tissue research has become widely developed in several
rheumatology centres, however, large discrepancies exist in the way synovial tissue is …

Synovial and serum B cell signature of autoantibody-negative rheumatoid arthritis vs autoantibody-positive rheumatoid arthritis and psoriatic arthritis

L De Stefano, S Bugatti, I Mazzucchelli, S Rossi… - …, 2024 - academic.oup.com
Objectives Autoantibody-negative RA differs from autoantibody-positive RA in several
clinical aspects, possibly underpinned by pathogenetic differences. At present, the role of …

The crucial questions on synovial biopsy: when, why, who, what, where, and how?

F Ingegnoli, LA Coletto, I Scotti, R Compagnoni… - Frontiers in …, 2021 - frontiersin.org
In the majority of joint diseases, changes in the organization of the synovial architecture
appear early. Synovial tissue analysis might provide useful information for the diagnosis …

Turning the page in osteoarthritis assessment with the use of ultrasound

AE Nelson - Current rheumatology reports, 2020 - Springer
Abstract Purpose of Review This narrative review summarizes the last 5 years of published,
peer-reviewed research on the use of musculoskeletal ultrasound (US) in osteoarthritis (OA) …

Synovial biopsies in clinical practice and research: current developments and perspectives

H Johnsson, A Najm - Clinical Rheumatology, 2021 - Springer
Synovial biopsy techniques have developed and widely expanded over the past few years,
in particular due to the development of ultrasound-guided procedures. This article reviews …