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Needle biopsy adequacy in the era of precision medicine and value-based health care
Context.—Needle biopsy of diseased tissue is an essential diagnostic tool that is becoming
even more important as precision medicine develops. However, the capability of this …
even more important as precision medicine develops. However, the capability of this …
Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis
Psoriatic arthritis (PsA) is a debilitating immune-mediated inflammatory arthritis of unknown
pathogenesis commonly affecting patients with skin psoriasis. Here we use complementary …
pathogenesis commonly affecting patients with skin psoriasis. Here we use complementary …
Synovial biopsies for molecular definition of rheumatoid arthritis and treatment response phenoty**: where can we improve?
Introduction The extensive knowledge gained in the cellular and molecular mechanisms
underlying Rheumatoid Arthritis (RA) pathogenesis has led to therapeutic advances …
underlying Rheumatoid Arthritis (RA) pathogenesis has led to therapeutic advances …
B cell synovitis and clinical phenotypes in rheumatoid arthritis: relationship to disease stages and drug exposure
F Rivellese, F Humby, S Bugatti… - Arthritis & …, 2020 - Wiley Online Library
Objective To define the relationship of synovial B cells to clinical phenotypes at different
stages of disease evolution and drug exposure in rheumatoid arthritis (RA). Methods …
stages of disease evolution and drug exposure in rheumatoid arthritis (RA). Methods …
[HTML][HTML] The EFSUMB guidelines and recommendations for musculoskeletal ultrasound–part II: joint pathologies, pediatric applications, and guided procedures
E Naredo, SC Rodriguez-Garcia… - Ultraschall in der …, 2022 - thieme-connect.com
The second part of the Guidelines and Recommendations for Musculoskeletal Ultrasound
(MSUS), produced under the auspices of EFSUMB, following the same methodology as for …
(MSUS), produced under the auspices of EFSUMB, following the same methodology as for …
EULAR points to consider for minimal reporting requirements in synovial tissue research in rheumatology
Background Synovial tissue research has become widely developed in several
rheumatology centres, however, large discrepancies exist in the way synovial tissue is …
rheumatology centres, however, large discrepancies exist in the way synovial tissue is …
Synovial and serum B cell signature of autoantibody-negative rheumatoid arthritis vs autoantibody-positive rheumatoid arthritis and psoriatic arthritis
L De Stefano, S Bugatti, I Mazzucchelli, S Rossi… - …, 2024 - academic.oup.com
Objectives Autoantibody-negative RA differs from autoantibody-positive RA in several
clinical aspects, possibly underpinned by pathogenetic differences. At present, the role of …
clinical aspects, possibly underpinned by pathogenetic differences. At present, the role of …
The crucial questions on synovial biopsy: when, why, who, what, where, and how?
In the majority of joint diseases, changes in the organization of the synovial architecture
appear early. Synovial tissue analysis might provide useful information for the diagnosis …
appear early. Synovial tissue analysis might provide useful information for the diagnosis …
Turning the page in osteoarthritis assessment with the use of ultrasound
AE Nelson - Current rheumatology reports, 2020 - Springer
Abstract Purpose of Review This narrative review summarizes the last 5 years of published,
peer-reviewed research on the use of musculoskeletal ultrasound (US) in osteoarthritis (OA) …
peer-reviewed research on the use of musculoskeletal ultrasound (US) in osteoarthritis (OA) …
Synovial biopsies in clinical practice and research: current developments and perspectives
H Johnsson, A Najm - Clinical Rheumatology, 2021 - Springer
Synovial biopsy techniques have developed and widely expanded over the past few years,
in particular due to the development of ultrasound-guided procedures. This article reviews …
in particular due to the development of ultrasound-guided procedures. This article reviews …