Roadmap for metal nanoparticles in radiation therapy: Current status, translational challenges, and future directions

J Schuemann, AF Bagley, R Berbeco… - Physics in Medicine …, 2020 - iopscience.iop.org
This roadmap outlines the potential roles of metallic nanoparticles (MNPs) in the field of
radiation therapy. MNPs made up of a wide range of materials (from Titanium, Z= 22, to …

Chemical overview of gel dosimetry systems: a comprehensive review

MA Macchione, S Lechón Páez, MC Strumia… - Gels, 2022 - mdpi.com
Advances in radiotherapy technology during the last 25 years have significantly improved
both dose conformation to tumors and the preservation of healthy tissues, achieving almost …

Catalytic activity imperative for nanoparticle dose enhancement in photon and proton therapy

LRH Gerken, A Gogos, FHL Starsich, H David… - Nature …, 2022 - nature.com
Nanoparticle-based radioenhancement is a promising strategy for extending the therapeutic
ratio of radiotherapy. While (pre) clinical results are encouraging, sound mechanistic …

[HTML][HTML] First demonstration of the FLASH effect with ultrahigh dose rate high-energy X-rays

F Gao, Y Yang, H Zhu, JX Wang, D **ao, Z Zhou… - Radiotherapy and …, 2022 - Elsevier
Purpose This study aimed to evaluate whether high-energy X-rays (HEXs) of the PARTER
(platform for advanced radiotherapy research) platform built on CTFEL (Chengdu THz Free …

New frontiers in colorectal cancer treatment combining nanotechnology with photo-and radiotherapy

SC Freitas, D Sanderson, S Caspani, R Magalhães… - Cancers, 2023 - mdpi.com
Simple Summary Although colorectal cancer is the third most common type of cancer, its
treatment strategies still have room for improvement, as current techniques carry risks that …

Prospects of nanoparticle-based radioenhancement for radiotherapy

LRH Gerken, ME Gerdes, M Pruschy… - Materials horizons, 2023 - pubs.rsc.org
Radiotherapy is a key pillar of solid cancer treatment. Despite high level of conformal dose
deposition, radiotherapy is limited due to co-irradiation of organs-at risk and subsequent …

Ionizing radiation and complex DNA damage: quantifying the radiobiological damage using Monte Carlo simulations

KP Chatzipapas, P Papadimitroulas, D Emfietzoglou… - Cancers, 2020 - mdpi.com
Ionizing radiation is a common tool in medical procedures. Monte Carlo (MC) techniques are
widely used when dosimetry is the matter of investigation. The scientific community has …

STING Agonist delivered by neutrophil membrane-coated gold nanoparticles exerts synergistic tumor inhibition with radiotherapy

D Lu, W Li, J Tan, Y Li, W Mao, Y Zheng… - … Applied Materials & …, 2024 - ACS Publications
Radiotherapy (RT) is one of the major treatments for cancers and a promising initiator of
immune response. Gold nanoparticles are a promising radiosensitizer. In this study, we …

XPS examination of the chemical composition of PEGMUA‐coated gold nanoparticles

P Hepperle, A Herman, B Khanbabaee… - Particle & Particle …, 2022 - Wiley Online Library
A surface chemical analysis of 12 nm diameter gold nanoparticles (AuNPs) coated with
polyethylene glycol (PEG)‐11‐mercaptoundecanoic acid (MUA) is performed by means of X …

A review of recent advances in the modeling of nanoparticle radiosensitization with the Geant4-DNA toolkit

A Taheri, MU Khandaker, F Moradi… - Radiation Physics and …, 2023 - Elsevier
Metallic nanoparticles are promising agents for increasing the effectiveness of radiation
therapy by making cells more sensitive to radiation. High atomic number nanoparticles …