T cell engineering has changed the landscape of cancer immunotherapy. Chimeric antigen
receptor T cells have demonstrated a remarkable efficacy in the treatment of B cell …

Flexible and stretchable bioelectronics provides a biocompatible interface between
electronics and biological systems and has received tremendous attention for in situ …

The T cell receptor (TCR) complex is a naturally occurring antigen sensor that detects,
amplifies and coordinates cellular immune responses to epitopes derived from cell surface …

The accurate selection of neoantigens that bind to class I human leukocyte antigen (HLA)
and are recognized by autologous T cells is a crucial step in many cancer immunotherapy …

Circular RNAs (circRNAs) are covalently closed non-coding RNAs lacking the 5'cap and the
poly-A tail. Nevertheless, it has been demonstrated that certain circRNAs can undergo active …

The success of cancer immunotherapy depends in part on the strength of antigen
recognition by T cells. Here, we characterize the T cell receptor (TCR) functional (antigen …

Public neoantigens (NeoAgs) represent an elite class of shared cancer-specific epitopes
derived from recurrently mutated driver genes. Here we describe a high-throughput platform …

T cell receptor (TCR) gene therapy is a potent form of cellular immunotherapy in which
patient T cells are genetically engineered to express TCRs with defined tumor reactivity …

T cells have the ability to eliminate infected and cancer cells and play an essential role in
cancer immunotherapy. T cell activation is elicited by the binding of the T cell receptor (TCR) …

The immunopeptidome is the set of peptides presented by the major histocompatibility
complex (MHC) molecules, in humans also known as the human leukocyte antigen (HLA) …