Advances in chitosan and chitosan derivatives for biomedical applications in tissue engineering: an updated review

A Elizalde-Cárdenas, RM Ribas-Aparicio… - International Journal of …, 2024 - Elsevier
In recent years, chitosan (CS) has received much attention as a functional biopolymer for
various applications, especially in the biomedical field. It is a natural polysaccharide created …

Advances in preparation, biomedical, and pharmaceutical applications of chitosan-based gold, silver, and magnetic nanoparticles: a review

M Jiang, RH Althomali, SA Ansari, EAM Saleh… - International Journal of …, 2023 - Elsevier
During the last decades, the ever-increasing incidence of various diseases, like cancer, has
led to a high rate of death worldwide. On the other hand, conventional modalities (such as …

Exploring modified chitosan-based gene delivery technologies for therapeutic advancements

AD Gholap, HS Kapare, S Pagar, P Kamandar… - International Journal of …, 2024 - Elsevier
One of the critical steps in gene therapy is the successful delivery of the genes.
Immunogenicity and toxicity are major issues for viral gene delivery systems. Thus, non-viral …

Dual targeting pH responsive chitosan nanoparticles for enhanced active cellular internalization of gemcitabine in non-small cell lung cancer

K Kumar, SG Rawat, M Mishra, A Kumar… - International Journal of …, 2023 - Elsevier
Lung cancer (LC), related with the enhanced expression of epidermal growth factor receptor
(EGFR) and sialic acid binding receptors (glycan) brought about the development of EGFR …

[HTML][HTML] Nanoparticle-based drug delivery systems in inhaled therapy: improving respiratory medicine

E Cojocaru, OR Petriș, C Cojocaru - Pharmaceuticals, 2024 - mdpi.com
Inhaled nanoparticle (NP) therapy poses intricate challenges in clinical and
pharmacodynamic realms. Recent strides have revolutionized NP technology by enabling …

Nanocarrier-Mediated Drug Delivery via Inhalational Route for Lung Cancer Therapy: A Systematic and Updated Review

N Ara, A Hafeez - AAPS PharmSciTech, 2024 - Springer
Lung cancer is one of the most severe lethal malignancies, with approximately 1.6 million
deaths every year. Lung cancer can be broadly categorised into small and non-small-cell …

Exploring nalbuphine loaded chitosan nanoparticles for effective pain management through intranasal administration: a comparative study

K Khanna, N Sharma, R Karwasra, A Kumar… - Journal of Drug …, 2025 - Taylor & Francis
Background Intranasal drug delivery shows potential for brain access via olfactory and
trigeminal routes. Purpose This work aimed to ensure brain availability of nalbuphine via the …

Recent progress in cancer immunotherapy: Application of nano-therapeutic systems

R Ghafelehbashi, M Salehi, M Kouhi… - Journal of Drug Delivery …, 2024 - Elsevier
Cancer immunotherapy is a hopeful strategy that seeks to enhance the immune system's
capacity to detect, manage, and eradicate cancerous cells. It has shown promise in halting …

Glutathione (GSH)-responsive gold nanoparticles effectively delivered nisin for enhanced cytotoxicity in lung cancer cells

K Saravanakumar, SJ Park, Z Li, L Yao, Y Kim… - Journal of Drug Delivery …, 2024 - Elsevier
Lung cancer remains one of the leading causes of cancer-related deaths worldwide,
highlighting the urgent need for more effective and targeted therapies. In this study, we …

[HTML][HTML] Chitosan as a Plurivalent Biopolymer in Nanodelivery Systems

MG Dabija, I Olaru, T Ciuhodaru, A Stefanache… - Polymers, 2025 - mdpi.com
(1) Background: This review study will delve into the potential of chitosan nanoparticles
(NPs) as adaptable carriers for targeted drug delivery in different therapeutic areas …