Flavin-based electron bifurcation, a new mechanism of biological energy coupling

W Buckel, RK Thauer - Chemical reviews, 2018 - ACS Publications
There are two types of electron bifurcation (EB), either quinone-or flavin-based
(QBEB/FBEB), that involve reduction of a quinone or flavin by a two-electron transfer and two …

Flavin-Based Electron Bifurcation, Ferredoxin, Flavodoxin, and Anaerobic Respiration With Protons (Ech) or NAD+ (Rnf) as Electron Acceptors: A Historical Review

W Buckel, RK Thauer - Frontiers in microbiology, 2018 - frontiersin.org
Flavin-based electron bifurcation is a newly discovered mechanism, by which a hydride
electron pair from NAD (P) H, coenzyme F420H2, H2, or formate is split by flavoproteins into …

Fe protein docking transduces conformational changes to MoFe nitrogenase active site in a nucleotide-dependent manner

M Tokmina-Lukaszewska, Q Huang, L Berry… - Communications …, 2023 - nature.com
The reduction of dinitrogen to ammonia catalyzed by nitrogenase involves a complex series
of events, including ATP hydrolysis, electron transfer, and activation of metal clusters for N2 …

A new era for electron bifurcation

JW Peters, DN Beratan, B Bothner, RB Dyer… - Current opinion in …, 2018 - Elsevier
Highlights•Electron bifurcation couples endergonic and exergonic electron transfer
reactions.•Electron bifurcation requires redox sites capable of managing single and pairwise …

Unsteady magnetohydrodynamic free convection flow of nanofluid through an exponentially accelerated inclined plate embedded in a porous medium with variable …

SF Ahmmed, R Biswas, M Afikuzzaman - Journal of Nanofluids, 2018 - ingentaconnect.com
MHD (Magnetohydrodynamic) unsteady free convection flow of viscous nanofluid through
an exponentially accelerated inclined porous plate with variable viscosity and thermal …

Fatty acid allosteric regulation of CH activation in plant and animal lipoxygenases

AR Offenbacher, TR Holman - Molecules, 2020 - mdpi.com
Lipoxygenases (LOXs) catalyze the (per) oxidation of fatty acids that serve as important
mediators for cell signaling and inflammation. These reactions are initiated by a CH …

The catalytic mechanism of electron-bifurcating electron transfer flavoproteins (ETFs) involves an intermediary complex with NAD+

GJ Schut, N Mohamed-Raseek… - Journal of Biological …, 2019 - ASBMB
Electron bifurcation plays a key role in anaerobic energy metabolism, but it is a relatively
new discovery, and only limited mechanistic information is available on the diverse enzymes …

An uncharacteristically low-potential flavin governs the energy landscape of electron bifurcation

CE Wise, AE Ledinina, DW Mulder… - Proceedings of the …, 2022 - National Acad Sciences
Electron bifurcation, an energy-conserving process utilized extensively throughout all
domains of life, represents an elegant means of generating high-energy products from …

Iron-sulfur flavoenzymes: the added value of making the most ancient redox cofactors and the versatile flavins work together

MA Vanoni - Open biology, 2021 - royalsocietypublishing.org
Iron-sulfur (Fe-S) flavoproteins form a broad and growing class of complex, multi-domain
and often multi-subunit proteins coupling the most ancient cofactors (the Fe-S clusters) and …

Distribution, Evolution, Catalytic Mechanism, and Physiological Functions of the Flavin-Based Electron-Bifurcating NADH-Dependent Reduced Ferredoxin: NADP+ …

J Liang, H Huang, S Wang - Frontiers in microbiology, 2019 - frontiersin.org
NADH-dependent reduced ferredoxin: NADP+ oxidoreductase (Nfn) is an electron-
bifurcating enzyme first discovered in the strict anaerobes Clostridium kluyveri and Moorella …