[HTML][HTML] Sarcopenia and heart failure

F Curcio, G Testa, I Liguori, M Papillo, V Flocco… - Nutrients, 2020 - mdpi.com
Modifications of lean mass are a frequent critical determinant in the pathophysiology and
progression of heart failure (HF). Sarcopenia may be considered one of the most important …

Factors mediating spaceflight-induced skeletal muscle atrophy

PHU Lee, M Chung, Z Ren… - American Journal of …, 2022 - journals.physiology.org
Skeletal muscle atrophy is a well-known consequence of spaceflight. Because of the
potential significant impact of muscle atrophy and muscle dysfunction on astronauts and …

Muscle contractile and metabolic dysfunction is a common feature of sarcopenia of aging and chronic diseases: from sarcopenic obesity to cachexia

G Biolo, T Cederholm, M Muscaritoli - Clinical nutrition, 2014 - Elsevier
Skeletal muscle is the most abundant body tissue accounting for many physiological
functions. However, muscle mass and functions are not routinely assessed. Sarcopenia is …

Television viewing and time spent sedentary in relation to cancer risk: a meta-analysis

D Schmid, MF Leitzmann - JNCI: Journal of the National Cancer …, 2014 - academic.oup.com
Background Sedentary behavior is emerging as an independent risk factor for chronic
disease and mortality. However, the evidence relating television (TV) viewing and other …

Myokines in insulin resistance and type 2 diabetes

K Eckardt, SW Görgens, S Raschke, J Eckel - Diabetologia, 2014 - Springer
Skeletal muscle represents the largest organ of the body in non-obese individuals and is
now considered to be an active endocrine organ releasing a host of so-called myokines …

Age‐related differences in lean mass, protein synthesis and skeletal muscle markers of proteolysis after bed rest and exercise rehabilitation

RE Tanner, LB Brunker, J Agergaard… - The Journal of …, 2015 - Wiley Online Library
Key points Five days of bed rest resulted in a reduction in leg lean mass and strength in
older adults. After bed rest, older (but not younger) adults had reduced amino acid‐induced …

New insights into the pathogenesis and treatment of sarcopenia in chronic heart failure

J Yin, X Lu, Z Qian, W Xu, X Zhou - Theranostics, 2019 - pmc.ncbi.nlm.nih.gov
Sarcopenia is an age-related geriatric syndrome that is characterized by a progressive loss
of muscle mass, strength and function. Chronic heart failure (CHF), the final stage of various …

TAK-242, a specific inhibitor of Toll-like receptor 4 signalling, prevents endotoxemia-induced skeletal muscle wasting in mice

Y Ono, Y Maejima, M Saito, K Sakamoto, S Horita… - Scientific reports, 2020 - nature.com
Circulating lipopolysaccharide (LPS) concentrations are often elevated in patients with
sepsis or various endogenous diseases related to bacterial translocation from the gut …

[HTML][HTML] Cancer cachexia and related metabolic dysfunction

GWP Fonseca, J Farkas, E Dora… - International journal of …, 2020 - mdpi.com
Cancer cachexia is a complex multifactorial syndrome marked by a continuous depletion of
skeletal muscle mass associated, in some cases, with a reduction in fat mass. It is …

The pathogenetic bases of sarcopenia

SL Budui, AP Rossi, M Zamboni - Clinical Cases in Mineral …, 2015 - pmc.ncbi.nlm.nih.gov
Aging is accompanied by involuntary loss of skeletal muscle mass, strength and function,
called sarcopenia. The mechanisms underlying the development of sarcopenia are not …