Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds

MS Bonkowski, DA Sinclair - Nature reviews Molecular cell biology, 2016 - nature.com
Abstract The sirtuins (SIRT1–7) are a family of nicotinamide adenine dinucleotide (NAD+)-
dependent deacylases with remarkable abilities to prevent diseases and even reverse …

Resveratrol and cardiovascular diseases

D Bonnefont-Rousselot - Nutrients, 2016 - mdpi.com
The increased incidence of cardiovascular diseases (CVDs) has stimulated research for
substances that could improve cardiovascular health. Among them, resveratrol (RES), a …

Contribution of red wine consumption to human health protection

L Snopek, J Mlcek, L Sochorova, M Baron, I Hlavacova… - Molecules, 2018 - mdpi.com
Wine consumption has been popular worldwide for many centuries. Based on in vitro and in
vivo studies, a certain amount of everyday wine consumption may prevent various chronic …

[HTML][HTML] Resveratrol: From enhanced biosynthesis and bioavailability to multitargeting chronic diseases

N Pannu, A Bhatnagar - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Resveratrol, a phytoalexin with a wide range of pharmacological properties is synthesised
by plants in response to stress, injury, infection or UV radiations. As it is a secondary …

[HTML][HTML] Resveratrol: how much wine do you have to drink to stay healthy?

S Weiskirchen, R Weiskirchen - Advances in Nutrition, 2016 - Elsevier
Resveratrol is a naturally occurring stilbene endowed with multiple health-promoting effects.
It is produced by certain plants including several dietary sources such as grapes, apples …

[HTML][HTML] Preclinical and clinical evidence for the role of resveratrol in the treatment of cardiovascular diseases

BNM Zordoky, IM Robertson, JRB Dyck - Biochimica et Biophysica Acta …, 2015 - Elsevier
Cardiovascular disease is the leading cause of death worldwide. Despite advancements in
diagnosis and treatment of cardiovascular disease, the incidence of cardiovascular disease …

[HTML][HTML] The pharmacology of resveratrol in animals and humans

EJ Park, JM Pezzuto - Biochimica et Biophysica Acta (BBA)-Molecular basis …, 2015 - Elsevier
In addition to thousands of research papers related to resveratrol (RSV), approximately 300
review articles have been published. Earlier research tended to focus on pharmacological …

The role of epigenetic modifications in human cancers and the use of natural compounds as epidrugs: Mechanistic pathways and pharmacodynamic actions

A Bouyahya, H Mechchate, L Oumeslakht, I Zeouk… - Biomolecules, 2022 - mdpi.com
Cancer is a complex disease resulting from the genetic and epigenetic disruption of normal
cells. The mechanistic understanding of the pathways involved in tumor transformation has …

Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs

JA McCubrey, K Lertpiriyapong… - Aging (Albany …, 2017 - pmc.ncbi.nlm.nih.gov
Natural products or nutraceuticals have been shown to elicit anti-aging, anti-cancer and
other health-enhancing effects. A key target of the effects of natural products may be the …

Potential role of olive oil phenolic compounds in the prevention of neurodegenerative diseases

J Rodríguez-Morató, L **cota, M Fitó, M Farré… - Molecules, 2015 - mdpi.com
Adherence to the Mediterranean Diet (MD) has been associated with a reduced incidence of
neurodegenerative diseases and better cognitive performance. Virgin olive oil, the main …