Guideline-based management of asthma focuses on disease severity and choosing the
appropriate medical therapy to control symptoms and reduce the risk of exacerbations …

There have been extensive developments on cellular and molecular mechanisms of
immune regulation in allergy, asthma, autoimmune diseases, tumor development, organ …

Immune response dynamics in coronavirus disease 2019 (COVID-19) and their severe
manifestations have largely been studied in circulation. Here, we examined the relationship …

Toll-like receptors (TLRs) are sensors that recognize molecular patterns from viruses,
bacteria, and fungi to initiate innate immune responses to invading pathogens. The …

Respiratory syncytial virus (RSV) infection has an estimated global incidence of 33 million
cases in children younger than 5 years, with 10% requiring hospital admission and up to …

Background Patients infected with the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), responsible for the coronavirus disease 2019 (COVID-19), exhibit a wide …

Viral respiratory tract infections are the main causative agents of the onset of infection-
induced asthma and asthma exacerbations that remain mechanistically unexplained. Here …

Sex differences in the incidence and severity of respiratory virus infection are widely
documented in humans and murine models and correlate with sex biases in numbers and/or …

Artificial Intelligence (AI) methods have significant potential for diagnosis and prognosis of
COVID-19 infections. Rapid identification of COVID-19 and its severity in individual patients …

The presented work summarizes the results of studies underlining the crucial role of
estrogen receptor (ER) signaling in both innate and adaptive immune responses as well as …