Droplet-based microfluidic systems generate, manipulate and control sub-microlitre droplets
enclosed within an immiscible carrier fluid. Owing to a number of remarkable features, such …

Novel and improved biocatalysts are increasingly sourced from libraries via experimental
screening. The success of such campaigns is crucially dependent on the number of …

Just as in clay moulding or glass blowing, physically sculpting biological structures requires
the constituent material to locally flow like a fluid while maintaining overall mechanical …

Droplet microfluidics generates and manipulates discrete droplets through immiscible
multiphase flows inside microchannels. Due to its remarkable advantages, droplet …

Digital Polymerase Chain Reaction (dPCR) is a novel method for the absolute quantification
of target nucleic acids. Quantification by dPCR hinges on the fact that the random …

Tissue morphogenesis, homoeostasis and repair require cells to constantly monitor their
three-dimensional microenvironment and adapt their behaviours in response to local …

We present a droplet-based microfluidics protocol for high-throughput analysis and sorting
of single cells. Compartmentalization of single cells in droplets enables the analysis of …

With remarkable precision and reproducibility, cells orchestrate the cooperative action of
thousands of nanometre-sized molecular motors to carry out mechanical tasks at much …

Precise, tunable emulsions and foams produced in microfluidic geometries have found wide
application in biochemical analysis and materials synthesis and characterization. Superb …

Existing techniques to encapsulate cells into microscale hydrogels generally yield high
polymer-to-cell ratios and lack control over the hydrogel's mechanical properties. Here, we …