Growth factor engineering strategies for regenerative medicine applications

X Ren, M Zhao, B Lash, MM Martino… - … in bioengineering and …, 2020 - frontiersin.org
Growth factors are critical molecules for tissue repair and regeneration. Therefore,
recombinant growth factors have raised a lot of hope for regenerative medicine applications …

[HTML][HTML] Advances in keratinocyte delivery in burn wound care

B Ter Horst, G Chouhan, NS Moiemen… - Advanced drug delivery …, 2018 - Elsevier
This review gives an updated overview on keratinocyte transplantation in burn wounds
concentrating on application methods and future therapeutic cell delivery options with a …

Novel biomaterial strategies for controlled growth factor delivery for biomedical applications

Z Wang, Z Wang, WW Lu, W Zhen, D Yang… - NPG Asia …, 2017 - nature.com
Growth factors (GFs) are soluble proteins secreted by cells that have the ability to regulate a
variety of cellular processes and tissue regeneration. However, their translation into clinical …

[HTML][HTML] Growth factor delivery using extracellular matrix-mimicking substrates for musculoskeletal tissue engineering and repair

RCH Gresham, CS Bahney, JK Leach - Bioactive Materials, 2021 - Elsevier
Therapeutic approaches for musculoskeletal tissue regeneration commonly employ growth
factors (GFs) to influence neighboring cells and promote migration, proliferation, or …

Platelet-rich plasma: a comparative and economical therapy for wound healing and tissue regeneration

R Verma, S Kumar, P Garg, YK Verma - Cell and Tissue Banking, 2023 - Springer
Rise in the incidences of chronic degenerative diseases with aging makes wound care a
socio-economic burden and unceasingly necessitates a novel, economical, and efficient …

Steroid-induced osteonecrosis of the femoral head: novel insight into the roles of bone endothelial cells in pathogenesis and treatment

C Huang, Z Wen, J Niu, S Lin, W Wang - Frontiers in cell and …, 2021 - frontiersin.org
Steroid-induced osteonecrosis of the femoral head (SONFH) is a disease characterized by
the collapse of the femoral head. SONFH occurs due to the overuse of glucocorticoids (GCs) …

Growth factor and cytokine delivery systems for wound healing

JMD Legrand, MM Martino - Cold Spring Harbor …, 2022 - cshperspectives.cshlp.org
Skin wound healing is a highly coordinated process involving multiple tissue-resident and
recruited cell types. Cells within the wound microenvironment respond to key secreted …

Advances in fibrin-based materials in wound repair: a review

IS Bayer - Molecules, 2022 - mdpi.com
The first bioprocess that occurs in response to wounding is the deterrence of local
hemorrhage. This is accomplished by platelet aggregation and initiation of the hemostasis …

Fibrin-based delivery strategies for acute and chronic wound healing

P Heher, S Mühleder, R Mittermayr, H Redl… - Advanced drug delivery …, 2018 - Elsevier
Fibrin, a natural hydrogel, is the end product of the physiological blood coagulation cascade
and naturally involved in wound healing. Beyond its role in hemostasis, it acts as a local …

Biomaterials for sequestration of growth factors and modulation of cell behavior

SPB Teixeira, RMA Domingues… - Advanced Functional …, 2020 - Wiley Online Library
Growth factors (GFs) are proteins secreted by cells that regulate a variety of biological
processes. Although they have long been proposed as potent therapeutic agents, their …