[HTML][HTML] Regulation of protein prenylation

D Jung, HS Bachmann - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Prenyltransferases (PTases) are known to play a role in embryonic development, normal
tissue homeostasis and cancer by posttranslationally modifying proteins involved in these …

Farnesyl pyrophosphate synthase: a key enzyme in isoprenoid biosynthetic pathway and potential molecular target for drug development

MK Dhar, A Koul, S Kaul - New biotechnology, 2013 - Elsevier
As isoprenoid biosynthetic pathway has gained importance since last few years, key
enzymes of this pathway have been characterized and their functional roles in the cell …

Unbiased analysis of pancreatic cancer radiation resistance reveals cholesterol biosynthesis as a novel target for radiosensitisation

JJ Souchek, MJ Baine, C Lin, S Rachagani… - British journal of …, 2014 - nature.com
Background: Despite its promise as a highly useful therapy for pancreatic cancer (PC), the
addition of external beam radiation therapy to PC treatment has shown varying success in …

Functional characterization of a farnesyl diphosphate synthase from Dendrobium nobile Lindl

D Gong, B Wu, H Qin, D Fu, S Guo, B Wang, B Li - Amb Express, 2022 - Springer
Dendrobium nobile Lindl. has been used as a traditional Chinese medicine for a long time,
in which the most important compound is dendrobine functioning in a variety of …

The integrative method based on the module-network for identifying driver genes in cancer subtypes

X Lu, X Li, P Liu, X Qian, Q Miao, S Peng - Molecules, 2018 - mdpi.com
With advances in next-generation sequencing (NGS) technologies, a large number of
multiple types of high-throughput genomics data are available. A great challenge in …

Human lineage-specific transcriptional regulation through GA-binding protein transcription factor alpha (GABPa)

A Perdomo-Sabogal, K Nowick, I Piccini… - Molecular biology …, 2016 - academic.oup.com
A substantial fraction of phenotypic differences between closely related species are likely
caused by differences in gene regulation. While this has already been postulated over 30 …

The rs1001179 SNP and CpG methylation regulate catalase expression in chronic lymphocytic leukemia

M Galasso, E Dalla Pozza, R Chignola… - Cellular and Molecular …, 2022 - Springer
Chronic lymphocytic leukemia (CLL) is an incurable disease characterized by an extremely
variable clinical course. We have recently shown that high catalase (CAT) expression …

Circular RNA expression profiles in the porcine liver of two distinct phenotype pig breeds

M Huang, Y Shen, H Mao, L Chen… - … journal of animal …, 2017 - pmc.ncbi.nlm.nih.gov
Objective An experiment was conducted to identify and characterize the circular RNA
expression and metabolic characteristics in the liver of **hua pigs and Landrace pigs …

Association of farnesyl diphosphate synthase polymorphisms and response to alendronate treatment in Chinese postmenopausal women with osteoporosis

Y Liu, H Liu, M Li, P Zhou, X **ng, W **a… - Chinese medical …, 2014 - journals.lww.com
Background Genetic factors are important in the pathogenesis of osteoporosis, but less is
known about the genetic determinants of osteoporosis treatment. We aimed to explore the …

Identification of suitable mRNAs and microRNAs as reference genes for expression analyses in skin cells under sex hormone exposure

S Fochi, E Orlandi, L Ceccuzzi, M Rodolfo, E Vergani… - Gene, 2021 - Elsevier
Quantitative RT-PCR is the most accurate technique for the study of gene expression
profiles, however, to ensure the accuracy of qPCR results, suitable reference genes are …