[HTML][HTML] Regulation of protein prenylation
D Jung, HS Bachmann - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Prenyltransferases (PTases) are known to play a role in embryonic development, normal
tissue homeostasis and cancer by posttranslationally modifying proteins involved in these …
tissue homeostasis and cancer by posttranslationally modifying proteins involved in these …
Farnesyl pyrophosphate synthase: a key enzyme in isoprenoid biosynthetic pathway and potential molecular target for drug development
As isoprenoid biosynthetic pathway has gained importance since last few years, key
enzymes of this pathway have been characterized and their functional roles in the cell …
enzymes of this pathway have been characterized and their functional roles in the cell …
Unbiased analysis of pancreatic cancer radiation resistance reveals cholesterol biosynthesis as a novel target for radiosensitisation
Background: Despite its promise as a highly useful therapy for pancreatic cancer (PC), the
addition of external beam radiation therapy to PC treatment has shown varying success in …
addition of external beam radiation therapy to PC treatment has shown varying success in …
Functional characterization of a farnesyl diphosphate synthase from Dendrobium nobile Lindl
D Gong, B Wu, H Qin, D Fu, S Guo, B Wang, B Li - Amb Express, 2022 - Springer
Dendrobium nobile Lindl. has been used as a traditional Chinese medicine for a long time,
in which the most important compound is dendrobine functioning in a variety of …
in which the most important compound is dendrobine functioning in a variety of …
The integrative method based on the module-network for identifying driver genes in cancer subtypes
X Lu, X Li, P Liu, X Qian, Q Miao, S Peng - Molecules, 2018 - mdpi.com
With advances in next-generation sequencing (NGS) technologies, a large number of
multiple types of high-throughput genomics data are available. A great challenge in …
multiple types of high-throughput genomics data are available. A great challenge in …
Human lineage-specific transcriptional regulation through GA-binding protein transcription factor alpha (GABPa)
A substantial fraction of phenotypic differences between closely related species are likely
caused by differences in gene regulation. While this has already been postulated over 30 …
caused by differences in gene regulation. While this has already been postulated over 30 …
The rs1001179 SNP and CpG methylation regulate catalase expression in chronic lymphocytic leukemia
M Galasso, E Dalla Pozza, R Chignola… - Cellular and Molecular …, 2022 - Springer
Chronic lymphocytic leukemia (CLL) is an incurable disease characterized by an extremely
variable clinical course. We have recently shown that high catalase (CAT) expression …
variable clinical course. We have recently shown that high catalase (CAT) expression …
Circular RNA expression profiles in the porcine liver of two distinct phenotype pig breeds
M Huang, Y Shen, H Mao, L Chen… - … journal of animal …, 2017 - pmc.ncbi.nlm.nih.gov
Objective An experiment was conducted to identify and characterize the circular RNA
expression and metabolic characteristics in the liver of **hua pigs and Landrace pigs …
expression and metabolic characteristics in the liver of **hua pigs and Landrace pigs …
Association of farnesyl diphosphate synthase polymorphisms and response to alendronate treatment in Chinese postmenopausal women with osteoporosis
Y Liu, H Liu, M Li, P Zhou, X **ng, W **a… - Chinese medical …, 2014 - journals.lww.com
Background Genetic factors are important in the pathogenesis of osteoporosis, but less is
known about the genetic determinants of osteoporosis treatment. We aimed to explore the …
known about the genetic determinants of osteoporosis treatment. We aimed to explore the …
Identification of suitable mRNAs and microRNAs as reference genes for expression analyses in skin cells under sex hormone exposure
S Fochi, E Orlandi, L Ceccuzzi, M Rodolfo, E Vergani… - Gene, 2021 - Elsevier
Quantitative RT-PCR is the most accurate technique for the study of gene expression
profiles, however, to ensure the accuracy of qPCR results, suitable reference genes are …
profiles, however, to ensure the accuracy of qPCR results, suitable reference genes are …