[HTML][HTML] Mitochondria and brain disease: a comprehensive review of pathological mechanisms and therapeutic opportunities

VJ Clemente-Suárez, L Redondo-Flórez… - Biomedicines, 2023 - mdpi.com
Mitochondria play a vital role in maintaining cellular energy homeostasis, regulating
apoptosis, and controlling redox signaling. Dysfunction of mitochondria has been implicated …

Caught in vicious circles: a perspective on dynamic feed-forward loops driving oxidative stress in schizophrenia

M Cuenod, P Steullet, JH Cabungcal, D Dwir… - Molecular …, 2022 - nature.com
A growing body of evidence has emerged demonstrating a pathological link between
oxidative stress and schizophrenia. This evidence identifies oxidative stress as a …

Single-atom nanozymes with peroxidase-like activity: A review

EM Hamed, V Rai, SFY Li - Chemosphere, 2024 - Elsevier
Single-atom nanozymes (SANs) are nanomaterials-based nanozymes with atomically
dispersed enzyme-like active sites. SANs offer improved as well as tunable catalytic activity …

Nutritional composition of hass avocado pulp

NA Ford, P Spagnuolo, J Kraft, E Bauer - Foods, 2023 - mdpi.com
Avocados (Persea americana) are a unique fruit that can provide health benefits when
included in a healthy diet. As health care moves towards precision health and targeted …

[HTML][HTML] Oxidative stress and psychiatric disorders: evidence from the bidirectional mendelian randomization study

Z Lu, C Pu, Y Zhang, Y Sun, Y Liao, Z Kang, X Feng… - Antioxidants, 2022 - mdpi.com
Observational studies have shown that oxidative stress is highly related to psychiatric
disorders, while its cause–effect remains unclear. To this end, a Mendelian randomization …

Hippocampal circuit dysfunction in psychosis

S Knight, R McCutcheon, D Dwir, AA Grace… - Translational …, 2022 - nature.com
Despite strong evidence of the neurodevelopmental origins of psychosis, current
pharmacological treatment is not usually initiated until after a clinical diagnosis is made, and …

[HTML][HTML] Oxidative stress and emergence of psychosis

V Rambaud, A Marzo, B Chaumette - Antioxidants, 2022 - mdpi.com
Treatment and prevention strategies for schizophrenia require knowledge about the
mechanisms involved in the psychotic transition. Increasing evidence suggests a redox …

MicroRNAs in the Onset of Schizophrenia

KT Thomas, SS Zakharenko - Cells, 2021 - mdpi.com
Mounting evidence implicates microRNAs (miRNAs) in the pathology of schizophrenia.
These small noncoding RNAs bind to mRNAs containing complementary sequences and …

Fluorescent sensing of glutathione and related bio-applications

X Sun, F Guo, Q Ye, J Zhou, J Han, R Guo - Biosensors, 2022 - mdpi.com
Glutathione (GSH), as the most abundant low-molecular-weight biological thiol, plays
significant roles in vivo. Abnormal GSH levels have been demonstrated to be related to the …

Schizophrenia synaptic pathology and antipsychotic treatment in the framework of oxidative and mitochondrial dysfunction: translational highlights for the clinics and …

G De Simone, B Mazza, L Vellucci, A Barone… - Antioxidants, 2023 - mdpi.com
Schizophrenia is a worldwide mental illness characterized by alterations at dopaminergic
and glutamatergic synapses resulting in global dysconnectivity within and between brain …