Technological innovations in photochemistry for organic synthesis: flow chemistry, high-throughput experimentation, scale-up, and photoelectrochemistry

L Buglioni, F Raymenants, A Slattery… - Chemical …, 2021 - ACS Publications
Photoinduced chemical transformations have received in recent years a tremendous amount
of attention, providing a plethora of opportunities to synthetic organic chemists. However …

Late-stage C–H functionalization offers new opportunities in drug discovery

L Guillemard, N Kaplaneris, L Ackermann… - Nature Reviews …, 2021 - nature.com
Over the past decade, the landscape of molecular synthesis has gained major impetus by
the introduction of late-stage functionalization (LSF) methodologies. C–H functionalization …

Advances on the merger of electrochemistry and transition metal catalysis for organic synthesis

CA Malapit, MB Prater, JR Cabrera-Pardo, M Li… - Chemical …, 2021 - ACS Publications
Synthetic organic electrosynthesis has grown in the past few decades by achieving many
valuable transformations for synthetic chemists. Although electrocatalysis has been popular …

Organic electrochemistry: molecular syntheses with potential

C Zhu, NWJ Ang, TH Meyer, Y Qiu… - ACS central …, 2021 - ACS Publications
Efficient and selective molecular syntheses are paramount to inter alia biomolecular
chemistry and material sciences as well as for practitioners in chemical, agrochemical, and …

Strategic evolution in transition metal-catalyzed directed C–H bond activation and future directions

S Rej, A Das, N Chatani - Coordination Chemistry Reviews, 2021 - Elsevier
In the field of C–H bond functionalization chemistry, directed C–H bond activation strategies
are highly appreciated due to the high efficiency and selectivity of such reactions towards a …

Traditional and sustainable approaches for the construction of C–C bonds by harnessing C–H arylation

J Grover, G Prakash, N Goswami, D Maiti - Nature Communications, 2022 - nature.com
Biaryl scaffolds are found in natural products and drug molecules and exhibit a wide range
of biological activities. In past decade, the transition metal-catalyzed C–H arylation reaction …

Visible-Light-Driven Catalytic Reductive Carboxylation with CO2

Z Zhang, JH Ye, T Ju, LL Liao, H Huang, YY Gui… - ACS …, 2020 - ACS Publications
Carbon dioxide (CO2) is an important C1 source for the generation of important carboxylic
acids and derivatives. Stoichiometric and catalytic carboxylation of nucleophiles, including …

3d metallaelectrocatalysis for resource economical syntheses

P Gandeepan, LH Finger, TH Meyer… - Chemical Society …, 2020 - pubs.rsc.org
Resource economy constitutes one of the key challenges for researchers and practitioners
in academia and industries, in terms of rising demand for sustainable and green synthetic …

Recent advances in transition metal-catalyzed olefinic C–H functionalization

B Liu, L Yang, P Li, F Wang, X Li - Organic Chemistry Frontiers, 2021 - pubs.rsc.org
Transition metal-catalyzed directed C–H activation has emerged as an increasingly powerful
tool for the synthesis of important organic building blocks, organic materials and natural …

The emergence of the C–H functionalization strategy in medicinal chemistry and drug discovery

R Jana, HM Begam, E Dinda - Chemical Communications, 2021 - pubs.rsc.org
Owing to the market competitiveness and urgent societal need, an optimum speed of drug
discovery is an important criterion for successful implementation. Despite the rapid ascent of …