Incipient and subclinical tuberculosis: a clinical review of early stages and progression of infection

PK Drain, KL Bajema, D Dowdy, K Dheda… - Clinical microbiology …, 2018 - Am Soc Microbiol
Tuberculosis (TB) is the leading infectious cause of mortality worldwide, due in part to a
limited understanding of its clinical pathogenic spectrum of infection and disease …

Antimicrobial resistance in Mycobacterium tuberculosis: mechanistic and evolutionary perspectives

SM Gygli, S Borrell, A Trauner… - FEMS microbiology …, 2017 - academic.oup.com
Antibiotic-resistant Mycobacterium tuberculosis strains are threatening progress in
containing the global tuberculosis epidemic. Mycobacterium tuberculosis is intrinsically …

A robust SNP barcode for ty** Mycobacterium tuberculosis complex strains

F Coll, R McNerney, JA Guerra-Assunção… - Nature …, 2014 - nature.com
Strain-specific genomic diversity in the Mycobacterium tuberculosis complex (MTBC) is an
important factor in pathogenesis that may affect virulence, transmissibility, host response …

[HTML][HTML] Consequences of genomic diversity in Mycobacterium tuberculosis

M Coscolla, S Gagneux - Seminars in immunology, 2014 - Elsevier
The causative agent of human tuberculosis, Mycobacterium tuberculosis complex (MTBC),
comprises seven phylogenetically distinct lineages associated with different geographical …

Robust barcoding and identification of Mycobacterium tuberculosis lineages for epidemiological and clinical studies

G Napier, S Campino, Y Merid, M Abebe… - Genome medicine, 2020 - Springer
Background Tuberculosis, caused by bacteria in the Mycobacterium tuberculosis complex
(MTBC), is a major global public health burden. Strain-specific genomic diversity in the …

Mycobacterium tuberculosis: ecology and evolution of a human bacterium

AL Banuls, A Sanou, NT Van Anh… - Journal of medical …, 2015 - microbiologyresearch.org
Some species of the Mycobacterium tuberculosis complex (MTBC), particularly
Mycobacterium tuberculosis, which causes human tuberculosis (TB), are the first cause of …

Large-scale whole genome sequencing of M. tuberculosis provides insights into transmission in a high prevalence area

JA Guerra-Assunção, AC Crampin, R Houben… - Elife, 2015 - elifesciences.org
To improve understanding of the factors influencing tuberculosis transmission and the role of
pathogen variation, we sequenced all available specimens from patients diagnosed over 15 …

Early alveolar macrophage response and IL-1R-dependent T cell priming determine transmissibility of Mycobacterium tuberculosis strains

A Lovey, S Verma, V Kaipilyawar… - Nature …, 2022 - nature.com
Mechanisms underlying variability in transmission of Mycobacterium tuberculosis strains
remain undefined. By characterizing high and low transmission strains of M. tuberculosis in …

Tuberculosis caused by Mycobacterium africanum: Knowns and unknowns

ML Silva, B Cá, NS Osório, PNS Rodrigues… - PLoS …, 2022 - journals.plos.org
Tuberculosis (TB), one of the deadliest threats to human health, is mainly caused by 2 highly
related and human-adapted bacteria broadly known as Mycobacterium tuberculosis and …

TbD1 deletion as a driver of the evolutionary success of modern epidemic Mycobacterium tuberculosis lineages

D Bottai, W Frigui, F Sayes, M Di Luca… - Nature …, 2020 - nature.com
Mycobacterium tuberculosis (Mtb) strains are classified into different phylogenetic lineages
(L), three of which (L2/L3/L4) emerged from a common progenitor after the loss of the …