Animal models of pulmonary hypertension: Getting to the heart of the problem
JP Dignam, TE Scott, BK Kemp‐Harper… - British Journal of …, 2022 - Wiley Online Library
Despite recent therapeutic advances, pulmonary hypertension (PH) remains a fatal disease
due to the development of right ventricular (RV) failure. At present, no treatments targeted at …
due to the development of right ventricular (RV) failure. At present, no treatments targeted at …
Chronic thromboembolic pulmonary Hypertension–What have we learned from large animal models
K Stam, S Clauss, YJHJ Taverne… - Frontiers in …, 2021 - frontiersin.org
Chronic thrombo-embolic pulmonary hypertension (CTEPH) develops in a subset of patients
after acute pulmonary embolism. In CTEPH, pulmonary vascular resistance, which is initially …
after acute pulmonary embolism. In CTEPH, pulmonary vascular resistance, which is initially …
Subject-specific one-dimensional fluid dynamics model of chronic thromboembolic pulmonary hypertension
Chronic thromboembolic pulmonary hypertension (CTEPH) develops due to the
accumulation of blood clots in the lung vasculature that obstructs flow and increases …
accumulation of blood clots in the lung vasculature that obstructs flow and increases …
Cardiac remodelling in a swine model of chronic thromboembolic pulmonary hypertension: comparison of right vs. left ventricle
K Stam, Z Cai, N van Der Velde… - The Journal of …, 2019 - Wiley Online Library
Key points Right ventricle (RV) function is the most important determinant of survival and
quality of life in patients with chronic thromboembolic pulmonary hypertension (CTEPH). The …
quality of life in patients with chronic thromboembolic pulmonary hypertension (CTEPH). The …
[HTML][HTML] Cell landscape atlas for patients with chronic thromboembolic pulmonary hypertension after pulmonary endarterectomy constructed using single-cell RNA …
R Miao, X Dong, J Gong, Y Li, X Guo, J Wang… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
This study aimed to construct an atlas of the cell landscape and comprehensively
characterize the cellular repertoire of the pulmonary endarterectomized tissues of patients …
characterize the cellular repertoire of the pulmonary endarterectomized tissues of patients …
Model of chronic thromboembolic pulmonary hypertension in rats caused by repeated intravenous administration of partially biodegradable sodium alginate …
AA Karpov, NA Anikin, AM Mihailova… - International Journal of …, 2021 - mdpi.com
Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare and life-threatening
complication of pulmonary embolism. As existing animal models of CTEPH do not fully …
complication of pulmonary embolism. As existing animal models of CTEPH do not fully …
[HTML][HTML] Mid-regional pro-atrial natriuretic peptide and copeptin as indicators of disease severity and therapy response in CTEPH
SD Kriechbaum, L Scherwitz… - ERJ Open …, 2020 - Eur Respiratory Soc
Background Chronic thromboembolic pulmonary hypertension (CTEPH) leads to right heart
failure. Pulmonary endarterectomy (PEA) or balloon pulmonary angioplasty (BPA) restore …
failure. Pulmonary endarterectomy (PEA) or balloon pulmonary angioplasty (BPA) restore …
Chronic thromboembolic pulmonary hypertension: the bench
Abstract Purpose of Review Chronic thromboembolic pulmonary hypertension (CTEPH) is
an uncommon complication of acute pulmonary embolism (PE), in which the red, platelet …
an uncommon complication of acute pulmonary embolism (PE), in which the red, platelet …
Establishment of adult right ventricle failure in ovine using a graded, animal‐specific pulmonary artery constriction model
M Nguyen‐Truong, W Liu, J Boon… - Animal Models and …, 2020 - Wiley Online Library
Background Right ventricle failure (RVF) is associated with serious cardiac and pulmonary
diseases that contribute significantly to the morbidity and mortality of patients. Currently, the …
diseases that contribute significantly to the morbidity and mortality of patients. Currently, the …
Markov Chain Monte Carlo with Gaussian Process Emulation for a 1D Hemodynamics Model of CTEPH
Microvascular disease is a contributor to persistent pulmonary hypertension in those with
chronic thromboembolic pulmonary hypertension (CTEPH). The heterogenous nature of the …
chronic thromboembolic pulmonary hypertension (CTEPH). The heterogenous nature of the …