[HTML][HTML] Exploring heterocyclic scaffolds in carbonic anhydrase inhibition: a decade of structural and therapeutic insights

N Naeem, A Sadiq, GA Othman, HM Yassin… - RSC …, 2024 - pubs.rsc.org
Heterocyclic compounds represent a prominent class of molecules with diverse
pharmacological activities. Among their therapeutic applications, they have gained …

Dmap-catalyzed synthesis of novel pyrrolo [2, 3-D] pyrimidine derivatives bearing an aromatic sulfonamide moiety

M Khashi, A Davoodnia, J Chamani - Phosphorus, Sulfur, and …, 2014 - Taylor & Francis
4-(N, N-Dimethylamino) pyridine (DMAP), with a dual role as a basic nucleophilic catalyst,
was shown to be a highly efficient catalyst for the synthesis of some new N-(2-aryl-7-benzyl …

Synthesis, characterization and in vitro inhibition of metal complexes of pyrazole based sulfonamide on human erythrocyte carbonic anhydrase isozymes I and II

N Büyükkıdan, B Büyükkıdan, M Bülbül… - Journal of Enzyme …, 2017 - Taylor & Francis
Sulfonamides represent an important class of biologically active compounds. A sulfonamide
possessing carbonic anhydrase (CA) inhibitory properties obtained from a pyrazole based …

Tautomerism in the sulfonamide moiety: synthesis, experimental and theoretical characterizations

Z Ettehadi, A Davoodnia, M Khashi… - Journal of Structural …, 2018 - Springer
Following our previous work, we synthesized N-(7-methyl-5, 6-diphenyl-2-m-tolyl-7 H-
pyrrolo [2, 3-d] pyrimidin-4-yl) benzensulfonamides to study the sulfonylimine-sulfonamide …

Synthesis and in vitro human carbonic anhydrase I and II inhibition properties of some novel hydrazone compounds containing an aryl sulfonate moiety

R Çakmak - Erzincan University Journal of Science and Technology, 2020 - dergipark.org.tr
The aim of this research was to evaluate the enzyme inhibitory potential of some new
hydrazone derivatives bearing an aryl sulfonate moiety against the human carbonic …

Synthesis, experimental and theoretical characterizations of some new pyrrolo [2, 3-d] pyrimidine derivatives bearing an aromatic sulfonamide moiety

M Khashi, SA Beyramabadi, A Davoodnia… - Journal of Molecular …, 2017 - Elsevier
Following our previous work, we newly synthesized and characterized some N-(7-methyl-2,
5, 6-triphenyl-7H-pyrrolo [2, 3-d] pyrimidin-4-yl) benzensulfonamides. Optimized geometries …

Microwave assisted solvent-free mannich bases: synthesis, characterization and effects of these compounds on HCA I and HCA II isozymes

B Büyükkıdan, N Büyükkıdan, M Bülbül… - Macedonian Journal of …, 2021 - mjcce.org.mk
Abstract Mannich bases (2a–d) of aromatic amines were synthesized by using a
conventional microwave technique under solvent-free conditions and characterized by IR …

Synthesis, Structural and Biological Studies of Some Metal Complexes derived from Tridentate Pyrazole-based Ligand

TM Musa, ZN Nasif… - Research Journal of …, 2020 - indianjournals.com
The new derivatives of heterocyclic resulting, studying spectral Cobalt (II), Nickel (II), Copper
(II), and Cadmium (II) with new tridentate ligand namely [3-(1-acetyl-4-[4-(dimethylamino) …