DNA nanotechnology has progressed from proof-of-concept demonstrations of structural
design towards application-oriented research. As a natural material with excellent self …

The breadth of structure and function displayed by the molecules of biology is remarkable.
Considering that there are only three major biopolymer backbones (proteins, ribonucleic …

Abstract Methicillin-Resistant Staphylococcus aureus (MRSA) induced infection calls for
antibacterial agents that are not prone to antimicrobial resistance. We prepare protease …

Certain proteins contain subunits that enable their active translocation across the plasma
membrane into cells. In the specific case of HIV-1, this subunit is the basic domain Tat49–57 …

One of the initial steps in the development of therapeutic agents is the identification of lead
compounds that bind to the receptor or enzyme target of interest. Many analogs of these …

Microbial infections endanger human health and life. Conventional antibiotics has saved
countless human lives, however, is seriously challenged by the quick emergence of …

During the last six years, combinatorial chemistry has attracted enormous attention from the
pharmaceutical industry because it can greatly facilitate the drug discovery process. 1 At the …

The administration of drugs, as a main challenge of pharmaceutical and medicinal
applications, has certainly benefited from the application of synthetic polymers. However …

Antimicrobial peptides (AMPs) and their mimics are emerging as promising antibiotic agents.
We present a library of “ampetoids”(antimicrobial peptoid oligomers) with helical structures …

Bioinspired polymeric materials are attracting increasing attention due to significant
advantages over their natural counterparts: the ability to precisely tune their structures over a …