The role that biomaterials play in the clinical treatment of damaged organs and tissues is
changing. While biomaterials used in permanent medical devices were required to passively …

Anchorage-dependent cells are of great interest for various biotechnological applications.(i)
They represent a formidable production means of viruses for vaccination purposes at very …

The cell microenvironment has a profound influence on the behaviour, growth and survival
of cells. The extracellular matrix (ECM) provides not only mechanical and structural support …

In pancreatic tissue engineering, generating human pancreatic islet organoids from stem
cells has been challenging due mainly to a poor understanding of niches required for …

Background Although umbilical cord blood (UCB) is identified as a source of mesenchymal
stem cells (MSCs) with various advantages, the success in cell isolation is volatile …

Inherent limitations of the traditional approaches to study brain function and disease, such
as rodent models and 2D cell culture platforms, have led to the development of 3D in vitro …

STUDY QUESTION Is it possible to derive a scaffold from human testis for the purpose of
tissue engineering and regenerative medicine? SUMMARY ANSWER We developed a …

Introduction Bone marrow-derived mesenchymal stem cells (BM-MSCs) for clinical use
should not be grown in media containing fetal bovine serum (FBS), because of serum …

This review describes recent developments regarding the use of natural and synthetic
polymers to support the propagation of human pluripotent stem cells (hPSCs), human …

Tissue-resident stem cells are surrounded by a microenvironment known as 'stem cell
niche'which is specific for each stem cell type. This niche comprises of cell-intrinsic and …