Enantioselective radical reactions using chiral catalysts

S Mondal, F Dumur, D Gigmes, MP Sibi… - Chemical …, 2022 - ACS Publications
Benefiting from the impressive increase in fundamental knowledge, the last 20 years have
shown a continuous burst of new ideas and consequently a plethora of new catalytic …

Catalytic enantioselective ring-opening reactions of cyclopropanes

V Pirenne, B Muriel, J Waser - Chemical Reviews, 2020 - ACS Publications
This review describes the development of enantioselective methods for the ring opening of
cyclopropanes. Both approaches based on the reaction of nonchiral cyclopropanes and …

Synthesis of azabicyclo [3.1. 1] heptenes enabled by catalyst-controlled annulations of bicyclo [1.1. 0] butanes with vinyl azides

Z Lin, H Ren, X Lin, X Yu, J Zheng - Journal of the American …, 2024 - ACS Publications
Bridged bicyclic scaffolds are emerging bioisosteres of planar aromatic rings under the
concept of “escape from flatland”. However, adopting this concept into the exploration of …

Photocatalyzed [2σ+ 2σ] and [2σ+ 2π] Cycloadditions for the Synthesis of Bicyclo [3.1. 1] heptanes and 5-or 6-Membered Carbocycles

TVT Nguyen, A Bossonnet, MD Wodrich… - Journal of the American …, 2023 - ACS Publications
We report the use of photocatalysis for the homolytic ring-opening of carbonyl
cyclopropanes. In contrast to previous studies, our approach does not require a metal …

Multiplicative enhancement of stereoenrichment by a single catalyst for deracemization of alcohols

L Wen, J Ding, L Duan, S Wang, Q An, H Wang, Z Zuo - Science, 2023 - science.org
Stereochemical enrichment of a racemic mixture by deracemization must overcome
unfavorable entropic effects as well as the principle of microscopic reversibility; recently …

Diboron (4)‐catalyzed remote [3+ 2] cycloaddition of cyclopropanes via dearomative/rearomative radical transmission through pyridine

M Xu, Z Wang, Z Sun, Y Ouyang, Z Ding… - Angewandte …, 2022 - Wiley Online Library
Ring structures such as pyridine, cyclopentane or their combinations are important motifs in
bioactive molecules. In contrast to previous cycloaddition reactions that necessitated a …

Asymmetric catalysis in radical chemistry

DA Nagib - Chemical Reviews, 2022 - ACS Publications
In our chiral world, the development of molecules that can improve our lives especially in
the areas of medicine and agriculture often requires enantioselective synthesis. In the past …

Exploiting attractive non-covalent interactions for the enantioselective catalysis of reactions involving radical intermediates

RSJ Proctor, AC Colgan, RJ Phipps - Nature Chemistry, 2020 - nature.com
The past decade has seen unprecedented growth in the development of new chemical
methods that proceed by mechanisms involving radical intermediates. This new attention …

Asymmetric catalytic reactions of donor–acceptor cyclopropanes

Y **a, X Liu, X Feng - Angewandte Chemie, 2021 - Wiley Online Library
Due to the synergistic “push–pull” effect of vicinal electron‐donating and electron‐
withdrawing groups, donor–acceptor (D‐A) cyclopropanes have been recognized as one of …

Titanium catalysis for the synthesis of fine chemicals–development and trends

M Manßen, LL Schafer - Chemical Society Reviews, 2020 - pubs.rsc.org
Titanium is the second most abundant transition metal and is already a key player in
important industrial processes (eg polyethylene). Titanium is an attractive metal to use for …