Natural approaches for the management of ulcerative colitis: evidence of preclinical and clinical investigations

RN Subudhi, N Poonia, D Singh, V Arora - Natural products and …, 2024 - Springer
Ulcerative colitis (UC) is a recurring autoimmune disorder characterized by persistent
inflammation in the mucosal lining of the lower part of the large intestine. Conventional …

Eimeria: Navigating complex intestinal ecosystems

S Weng, E Tian, M Gao, S Zhang, G Yang… - Plos …, 2024 - journals.plos.org
Eimeria is an intracellular obligate apicomplexan parasite that parasitizes the intestinal
epithelial cells of livestock and poultry, exhibiting strong host and tissue tropism. Parasite …

Perillyl alcohol attenuates rheumatoid arthritis via regulating TLR4/NF-κB and Keap1/Nrf2 signaling pathways: A comprehensive study onin-vitro and in-vivo …

ER Puppala, S Jain, P Saha, M Rachamalla… - Phytomedicine, 2022 - Elsevier
Background Rheumatoid arthritis is a chronic and idiopathic autoimmune disorder. Perillyl
alcohol (POH) is a monoterpene which can be extracted from widely available essential oils …

Perillyl alcohol attenuates chronic restraint stress aggravated dextran sulfate sodium-induced ulcerative colitis by modulating TLR4/NF-κB and JAK2/STAT3 signaling …

ER Puppala, SL Aochenlar, PA Shantanu, S Ahmed… - Phytomedicine, 2022 - Elsevier
Background Ulcerative colitis (UC) is the most prevalent chronic inflammatory immune
bowel disease. The modernization of lifestyle accompanied by the stress to cope with the …

Pivotal role of AKR1B1 in pathogenesis of colitis associated colorectal carcinogenesis

NP Syamprasad, B Rajdev, S Jain, SR Panda… - International …, 2023 - Elsevier
Identifying the target linking inflammation and oxidative stress to aggravate the disease
progression will help to prevent colitis associated carcinogenesis. Since AKR1B1 …

Loganic acid protects against ulcerative colitis by inhibiting TLR4/NF-κB mediated inflammation and activating the SIRT1/Nrf2 anti-oxidant responses in-vitro and in …

AN Prakash, N Prasad, ER Puppala, SR Panda… - International …, 2023 - Elsevier
Ulcerative colitis (UC) is an idiopathic, chronic disorder of the intestines characterized by
excessive inflammation and oxidative stress. Loganic acid (LA) is an iridoid glycoside …

Diosmin alleviates ulcerative colitis in mice by increasing Akkermansia muciniphila abundance, improving intestinal barrier function, and modulating the NF-κB and …

MB Salem, NM El-Lakkany, SHS El-Din, OA Hammam… - Heliyon, 2024 - cell.com
Ulcerative colitis is a common type of inflammatory bowel disease that affects millions of
individuals around the world. Traditional UC treatment has focused on suppressing immune …

Mesua assamica (King&Prain) kosterm. Bark ethanolic extract attenuates chronic restraint stress aggravated DSS-induced ulcerative colitis in mice via inhibition of NF …

ER Puppala, SS Yalamarthi, SL Aochenlar… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Mesua Assamica (King & prain) Kosterm.(MA) is
an evergreen endemic medicinal tree available in Assam in India and other parts of south …

Mesua assamica (King & Prain) kosterm. bark ethanolic extract attenuates rheumatoid arthritis via down-regulating TLR4/NF-κB/COX-2/iNOS and activation of Nrf2/HO …

ER Puppala, N Prasad, AN Prakash… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Rheumatoid arthritis (RA) is a multifactorial, polygenic
inflammatory disease. Mesua assamica (King & Prain) Kosterm.(MA) is an endangered …

A comparative analysis of the composition of the primary bioactive molecules, antioxidant activities, and anti-inflammation abilities of the roots of Zanthoxylum nitidum …

Y Yang, Y Liu, Y Yang, H Jia, P Tan, J Zeng… - Industrial Crops and …, 2024 - Elsevier
Zanthoxylum nitidum is a traditional medicinal herb prevalent in China and Southeast Asia.
However, despite being a widely cultivated perennial woody plant, an accurate reference …