Heart disease and stroke statistics—2018 update: a report from the American Heart Association

EJ Benjamin, SS Virani, CW Callaway… - Circulation, 2018 - ahajournals.org
Heart Disease and Stroke Statistics—2018 Update: A Report From the American Heart
Association | Circulation Skip to main content Become a member Volunteer Donate centennial Go …

[HTML][HTML] Cardiomyopathies: an overview

T Ciarambino, G Menna, G Sansone… - International journal of …, 2021 - mdpi.com
Background: Cardiomyopathies are a heterogeneous group of pathologies characterized by
structural and functional alterations of the heart. Aims: The purpose of this narrative review is …

Evidence-based assessment of genes in dilated cardiomyopathy

E Jordan, L Peterson, T Ai, B Asatryan, L Bronicki… - Circulation, 2021 - ahajournals.org
Background: Each of the cardiomyopathies, classically categorized as hypertrophic
cardiomyopathy, dilated cardiomyopathy (DCM), and arrhythmogenic right ventricular …

[HTML][HTML] ACMG SF v3. 2 list for reporting of secondary findings in clinical exome and genome sequencing: a policy statement of the American College of Medical …

DT Miller, K Lee, NS Abul-Husn, LM Amendola… - Genetics in …, 2023 - Elsevier
Disclaimer: This statement is designed primarily as an educational resource for medical
geneticists and other clinicians to help them provide quality medical services. Adherence to …

Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank

SJ Jurgens, SH Choi, VN Morrill, M Chaffin… - Nature …, 2022 - nature.com
Cardiometabolic diseases are the leading cause of death worldwide. Despite a known
genetic component, our understanding of these diseases remains incomplete. Here, we …

[HTML][HTML] The translational landscape of the human heart

S Van Heesch, F Witte, V Schneider-Lunitz, JF Schulz… - Cell, 2019 - cell.com
Gene expression in human tissue has primarily been studied on the transcriptional level,
largely neglecting translational regulation. Here, we analyze the translatomes of 80 human …

Dilated cardiomyopathy: genetic determinants and mechanisms

EM McNally, L Mestroni - Circulation research, 2017 - ahajournals.org
Nonischemic dilated cardiomyopathy (DCM) often has a genetic pathogenesis. Because of
the large number of genes and alleles attributed to DCM, comprehensive genetic testing …

Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect

R Tadros, C Francis, X Xu, AMC Vermeer, AR Harper… - Nature …, 2021 - nature.com
The heart muscle diseases hypertrophic (HCM) and dilated (DCM) cardiomyopathies are
leading causes of sudden death and heart failure in young, otherwise healthy, individuals …

Genetic variants associated with cancer therapy–induced cardiomyopathy

P Garcia-Pavia, Y Kim, MA Restrepo-Cordoba… - Circulation, 2019 - ahajournals.org
Background: Cancer therapy–induced cardiomyopathy (CCM) is associated with cumulative
drug exposures and preexisting cardiovascular disorders. These parameters incompletely …

Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy

JP Pirruccello, A Bick, M Wang, M Chaffin… - Nature …, 2020 - nature.com
Dilated cardiomyopathy (DCM) is an important cause of heart failure and the leading
indication for heart transplantation. Many rare genetic variants have been associated with …