Blood–Brain Barrier Breakdown in Neuroinflammation: Current In Vitro Models
S Brandl, M Reindl - International Journal of Molecular Sciences, 2023 - mdpi.com
The blood–brain barrier, which is formed by tightly interconnected microvascular endothelial
cells, separates the brain from the peripheral circulation. Together with other central nervous …
cells, separates the brain from the peripheral circulation. Together with other central nervous …
Nature-inspired solutions: A comprehensive review of biomimetic nanoparticles in nanomedicine
Biomimetic nanoparticles (BioM NPs) are an innovative strategy for nanomedicine
(NanoMed) that combines the advantages of artificial materials with the biological …
(NanoMed) that combines the advantages of artificial materials with the biological …
Albumin-binding photosensitizer capable of targeting glioma via the SPARC pathway
Background Malignant glioma is among the most lethal and frequently occurring brain
tumors, and the average survival period is 15 months. Existing chemotherapy has low …
tumors, and the average survival period is 15 months. Existing chemotherapy has low …
A Rapid-Patterning 3D Vessel-on-Chip for Imaging and Quantitatively Analyzing Cell–Cell Junction Phenotypes
The blood-brain barrier (BBB) is a dynamic interface that regulates the molecular exchanges
between the brain and peripheral blood. The permeability of the BBB is primarily regulated …
between the brain and peripheral blood. The permeability of the BBB is primarily regulated …
Environmental aluminum oxide inducing neurodegeneration in human neurovascular unit with immunity
Aluminum oxide nanoparticle (AlNP), a ubiquitous neurotoxin highly enriched in air
pollution, is often produced as an inevitable byproduct in the manufacturing of industrial …
pollution, is often produced as an inevitable byproduct in the manufacturing of industrial …
Advancing Central Nervous System Drug Delivery with Microtubule-Dependent Transcytosis of Novel Aqueous Compounds
M Zhang, S Zhong, L An, P **ang, N Hu… - Biomaterials …, 2024 - pmc.ncbi.nlm.nih.gov
The challenge of delivering therapeutics to the central nervous system due to the restrictive
nature of the blood–brain barrier (BBB) is a substantial hurdle in neuropharmacology. Our …
nature of the blood–brain barrier (BBB) is a substantial hurdle in neuropharmacology. Our …
[HTML][HTML] Mechanisms and Virulence Factors of Cryptococcus neoformans Dissemination to the Central Nervous System
AM Al-Huthaifi, BA Radman, AA Al-Alawi, F Mahmood… - Journal of Fungi, 2024 - mdpi.com
Cryptococcosis is a prevalent fungal infection of the central nervous system (CNS) caused
by Cryptococcus neoformans, a yeast with a polysaccharide capsule in the basidiomycete …
by Cryptococcus neoformans, a yeast with a polysaccharide capsule in the basidiomycete …
Cerebrovascular-Specific Extracellular Matrix Bioink Promotes Blood–Brain Barrier Properties
Chronic neuroinflammation is a principal cause of neurodegenerative diseases such as
Alzheimer's disease and Parkinson's disease. The blood–brain barrier predominantly …
Alzheimer's disease and Parkinson's disease. The blood–brain barrier predominantly …
Advancing Central Nervous System Drug Delivery with Microtubule-Dependent Transcytosis of Novel Aqueous Compounds
M Zhang, S Zhong, L An, P **ang, N Hu… - Biomaterials …, 2024 - spj.science.org
The challenge of delivering therapeutics to the central nervous system due to the restrictive
nature of the blood–brain barrier (BBB) is a substantial hurdle in neuropharmacology. Our …
nature of the blood–brain barrier (BBB) is a substantial hurdle in neuropharmacology. Our …
Tension at the gate: sensing mechanical forces at the blood–brain barrier in health and disease
CE Hansen, D Hollaus, A Kamermans… - Journal of …, 2024 - Springer
Microvascular brain endothelial cells tightly limit the entry of blood components and
peripheral cells into the brain by forming the blood–brain barrier (BBB). The BBB is …
peripheral cells into the brain by forming the blood–brain barrier (BBB). The BBB is …