Gap junctions are cell‐to‐cell junctions that are located in the basolateral surface of two
adjoining cells. A gap junction channel is composed of a family of proteins called connexins …

Melanoma is the most aggressive skin cancer, and in metastatic advanced states, it is
completely refractory to chemotherapy. Therefore, it is relevant to understand the molecular …

Connexins (Cxs) are a family of proteins that form two different types of ion channels:
hemichannels and gap junction channels. These channels participate in cellular …

Under normal conditions, almost all cell types communicate with their neighboring cells
through gap junction channels (GJC), facilitating cellular and tissue homeostasis. A GJC is …

Retinoblastoma is a rare childhood cancer of the eye. Of the small number of drugs are used
to treat retinoblastoma, all have been repurposed from drugs developed for other conditions …

Connexins are a family of proteins that can form two distinct types of channels:
hemichannels and gap junction channels. Hemichannels are composed of six connexin …

Connexins are the transmembrane proteins that form gap junctions between adjacent cells.
The function of the diverse connexin molecules is related to their tissue-specific expression …

Hemichannels (HCs) are hexamers of connexins that can form gap-junction channels at
points of cell contacts or" free HCs" at non-contacting regions. HCs are involved in paracrine …

Retinoblastoma (RB) is a malignant intra-ocular neoplasm that affects children (usually
below the age of 5 years). In addition to conventional chemotherapy, novel therapeutic …

Cancer is a widespread and incurable disease caused by genetic mutations, leading to
uncontrolled cell proliferation and metastasis. Connexins (Cx) are transmembrane proteins …