Epithelial–mesenchymal transition (EMT) is an essential process in normal embryonic
development and tissue regeneration. However, aberrant reactivation of EMT is associated …

Epithelial‐mesenchymal transition (EMT) is a complex process with a primordial role in
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …

MicroRNAs (miRNAs) are small, non-coding RNAs that post-transcriptionally regulate gene
expression by binding to specific mRNA targets and promoting their degradation and/or …

Cholangiocarcinoma (CCA) is an aggressive malignancy of the bile ducts, with poor
prognosis and limited treatment options. Here, we describe the integrated analysis of …

The transdifferentiation of epithelial cells into motile mesenchymal cells, a process known as
epithelial–mesenchymal transition (EMT), is integral in development, wound healing and …

The majority of the human genome is not translated into proteins but can be transcribed into
RNA. Even though the resulting non-coding RNAs (ncRNAs) do not encode for proteins …

Background and aims Hepatocellular carcinomas (HCCs) are heterogeneous aggressive
tumors with low rates of response to treatment at advanced stages. We screened a large …

Growing evidence links tumor progression with chronic inflammatory processes and
dysregulated activity of various immune cells. In this study, we demonstrate that various …

The epithelial to mesenchymal transition (EMT) is a powerful process in tumor invasion,
metastasis, and tumorigenesis and describes the molecular reprogramming and phenotypic …

Type 2 diabetes (T2D) is characterized by insulin resistance along with pancreatic β cell
failure. β cell factors are traditionally thought to control glucose homeostasis by modulating …