Many drugs, or their antecedents, were discovered through observation of their effects on
normal or disease physiology. For the past generation, this phenotypic drug discovery …

Drug designing and development is an important area of research for pharmaceutical
companies and chemical scientists. However, low efficacy, off-target delivery, time …

Prediction of chemical bioactivity and physical properties has been one of the most
important applications of statistical and more recently, machine learning and artificial …

COVID-19, the disease caused by the SARS-CoV-2 virus, has been declared a pandemic by
the World Health Organization, which has reported over 18 million confirmed cases as of …

Drug repositioning is the process of identifying novel therapeutic potentials for existing drugs
and discovering therapies for untreated diseases. Drug repositioning, therefore, plays an …

Abstract The Biological General Repository for Interaction Datasets (BioGRID:
https://thebiogrid. org) is an open access database dedicated to the curation and archival …

Abstract Background The SARS-CoV-2 pandemic is currently leading to increasing numbers
of COVID-19 patients all over the world. Clinical presentations range from asymptomatic …

Marine organisms are expected to be an important source of inspiration for drug discovery
after terrestrial plants and microorganisms. Despite the remarkable progress in the field of …

Without foreknowledge of the complete drug target information, development of promising
and affordable approaches for effective treatment of human diseases is challenging. Here …

This two‐part Review examines how automation has contributed to different aspects of
discovery in the chemical sciences. In this second part, we reflect on a selection of …