Hydrogels are one of the most commonly explored classes of biomaterials. Their chemical
and structural versatility has enabled their use across a wide range of applications, including …

The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

There is growing appreciation of the role that the extracellular environment plays in
regulating cell behavior. Mechanical, structural, and compositional cues, either alone or in …

The widespread multidrug resistance resulting from the abuse of antibiotics motivates
researchers to explore alternative methods to treat bacterial infections. Recently, the …

Photoactivated materials have found widespread use in biological and medical applications
and are playing an increasingly important role in the nascent field of three-dimensional (3D) …

Tumor cells evolve in a complex and heterogeneous environment composed of different cell
types and an extracellular matrix. Current 2D culture methods are very limited in their ability …

Understanding the spatiotemporal effects of surface topographies and modulated stiffness
and anisotropic stresses of hydrogels on cell growth remains a biophysical challenge. Here …

The biological compositions including cells, proteins/peptides, nucleic acids, extracellular
vesicles (EVs) and metabolites are no doubt closely related to almost all physiological and …

The cell microenvironment choreographs the behaviors of cells through multiple well-
controlled signals. For basic biological study and cell-based therapies, it is essential to …

Single cell analysis has become of great interest with unprecedented capabilities for the
systematic investigation of cell-to-cell variation in large populations. Rapid and multi …