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2022 update on prostate cancer epidemiology and risk factors—a systematic review
O Bergengren, KR Pekala, K Matsoukas, J Fainberg… - European urology, 2023 - Elsevier
Abstract Context Prostate cancer (PCa) is one of the most common cancers worldwide.
Understanding the epidemiology and risk factors of the disease is paramount to improve …
Understanding the epidemiology and risk factors of the disease is paramount to improve …
Recent advances in polygenic scores: translation, equitability, methods and FAIR tools
Polygenic scores (PGS) can be used for risk stratification by quantifying individuals' genetic
predisposition to disease, and many potentially clinically useful applications have been …
predisposition to disease, and many potentially clinically useful applications have been …
Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants
The transferability and clinical value of genetic risk scores (GRSs) across populations
remain limited due to an imbalance in genetic studies across ancestrally diverse …
remain limited due to an imbalance in genetic studies across ancestrally diverse …
Early prostate cancer deaths among men with higher vs lower genetic risk
A Plym, Y Zhang, KH Stopsack… - JAMA network …, 2024 - jamanetwork.com
Importance Prostate cancer, a leading cause of cancer death among men, urgently requires
new prevention strategies, which may involve targeting men with an underlying genetic …
new prevention strategies, which may involve targeting men with an underlying genetic …
Evidence of novel susceptibility variants for prostate cancer and a multiancestry polygenic risk score associated with aggressive disease in men of African ancestry
Background Genetic factors play an important role in prostate cancer (PCa) susceptibility.
Objective To discover common genetic variants contributing to the risk of PCa in men of …
Objective To discover common genetic variants contributing to the risk of PCa in men of …
Androgen receptor binding sites enabling genetic prediction of mortality due to prostate cancer in cancer-free subjects
Prostate cancer (PrCa) is the second most common cancer worldwide in males. While
strongly warranted, the prediction of mortality risk due to PrCa, especially before its …
strongly warranted, the prediction of mortality risk due to PrCa, especially before its …
Prostate Cancer Foundation screening guidelines for Black men in the United States
Abstract Background In the United States, Black men are at highest risk for being diagnosed
with and dying from prostate cancer. Given this disparity, we examined relevant data to …
with and dying from prostate cancer. Given this disparity, we examined relevant data to …
Heterogeneous genetic architectures of prostate cancer susceptibility in sub-Saharan Africa
Men of African descent have the highest prostate cancer incidence and mortality rates, yet
the genetic basis of prostate cancer in African men has been understudied. We used …
the genetic basis of prostate cancer in African men has been understudied. We used …
Polygenic scores in the direct-to-consumer setting: challenges and opportunities for a new era in consumer genetic testing
JK Park, CY Lu - Journal of Personalized Medicine, 2023 - mdpi.com
Direct-to-consumer (DTC) genetic tests have generated considerable scholarly attention and
public intrigue. Although the current consumer genetic testing regime relies on the reporting …
public intrigue. Although the current consumer genetic testing regime relies on the reporting …
Global viewpoints: updates on prostate cancer in Sub‐Saharan Africa
Prostate cancer (PCa) is a major health concern in Sub‐Saharan Africa (SSA), with high
incidence and mortality rates. However, the widely used prostate‐specific antigen (PSA) …
incidence and mortality rates. However, the widely used prostate‐specific antigen (PSA) …