Aging is a progressive and irreversible pathophysiological process that manifests as the
decline in tissue and cellular functions, along with a significant increase in the risk of various …

Osteoporosis is a common bone metabolic disease that causes a heavy social burden and
seriously threatens life. Improving osteogenic capacity is necessary to correct bone mass …

Introduction Osteoporosis is a systemic age-related disease characterized by reduced bone
mass and microstructure deterioration, leading to increased risk of bone fragility fractures …

Bone is constantly being remodeled, and this process is orchestrated by a dynamic crosstalk
of bone cells, including osteoclasts, osteoblasts, and osteocytes. Recent evidence suggests …

Adipose tissue is a dynamic component of the bone marrow, regulating skeletal remodelling
and secreting paracrine and endocrine factors that can affect haematopoiesis, as well as …

Bone marrow-derived mesenchymal stem cells (BMSCs) are promising candidates for cell-
based therapies. Growing evidence has indicated that overweight/obesity can change the …

Bone is a common site of metastasis for lung cancer. The “seed and soil” hypothesis
suggests that the bone marrow microenvironment (“soil”) may provide a conducive survival …

Lipid metabolism plays a crucial role in maintaining bone homeostasis, particularly in
osteoclasts (OCs) formation. Here, we found that the expression level of FATP2, a …

Metabolic dysfunction-associated steatohepatitis (MASH, previously termed non-alcoholic
steatohepatitis (NASH)), is a major complication of obesity that promotes fatty liver disease …

Adiposity and bone mineral density (BMD) are closely associated. The aim of this research
was to investigate the association between BMD and adiposity measures in adults, including …