It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

Intravitreal administration of drugs has raised a large interest during the last two decades
improving the treatment of infectious diseases of the posterior segment of the eye or …

Background: Intravitreal injection (IVI) with administration of various pharmacological agents
is a mainstay of treatment in ophthalmology for endopthalmitis, viral retinitis, age-related …

Effective drug delivery to the retina still remains a challenge due to ocular elimination
mechanisms and complex barriers that selectively limit the entry of drugs into the eye. To …

It is assumed that more than 50% of the most enfeebling ocular diseases have their origin in
the posterior segment. Furthermore, most of these diseases lead to partial or complete …

Purpose: To review the current state of evaluation and management of various forms of
endophthalmitis. Methods: A review of the literature is included, encompassing …

Endogenous fungal endophthalmitis, involving only the chorioretinal structures or extending
to involve the vitreous (vitritis), is a sight-threatening infection requiring early appropriate …

Infectious endophthalmitis is a severe intraocular infection caused by bacteria, or less
commonly by fungi. It can occur after penetrating eye procedures, trauma, or the spread of …

Poor drug delivery to lesions in patients' eyes is a major obstacle to the treatment of ocular
diseases. The accessibility of these areas to drugs is highly restricted by the presence of …

Polyenes and azoles constitute 2 major drug classes in the antifungal armamentarium used
to treat fungal infections of the eye such as fungal keratitis, endophthalmitis, conjunctivitis …