mRNA vaccines for infectious diseases—advances, challenges and opportunities
The concept of mRNA-based vaccines emerged more than three decades ago.
Groundbreaking discoveries and technological advancements over the past 20 years have …
Groundbreaking discoveries and technological advancements over the past 20 years have …
mRNA vaccines: The future of prevention of viral infections?
Messenger RNA (mRNA) vaccines against COVID‐19 are the first authorized biological
preparations developed using this platform. During the pandemic, their administration has …
preparations developed using this platform. During the pandemic, their administration has …
Single-dose mucosal replicon-particle vaccine protects against lethal Nipah virus infection up to 3 days after vaccination
Nipah virus (NiV) causes a highly lethal disease in humans who present with acute
respiratory or neurological signs. No vaccines against NiV have been approved to date …
respiratory or neurological signs. No vaccines against NiV have been approved to date …
Measures to prevent and treat Nipah virus disease: research priorities for 2024–29
KA Moore, AJ Mehr, JT Ostrowsky, AK Ulrich… - The Lancet Infectious …, 2024 - thelancet.com
Nipah virus causes highly lethal disease, with case-fatality rates ranging from 40% to 100%
in recognised outbreaks. No treatments or licensed vaccines are currently available for the …
in recognised outbreaks. No treatments or licensed vaccines are currently available for the …
Nipah virus–another threat from the world of zoonotic viruses
K Skowron, J Bauza-Kaszewska… - Frontiers in …, 2022 - frontiersin.org
Among the diseases that pose a serious threat to public health, those caused by viruses are
of great importance. The Nipah virus (NiV) belonging to the Paramyxoviridae family was …
of great importance. The Nipah virus (NiV) belonging to the Paramyxoviridae family was …
Principles and practical applications of structure-based vaccine design
Highlights•Summary of the basic principles of structure-based vaccine design.•Review of
recent advances (the years 2019–2021) in structure-based vaccine design.•Preview of …
recent advances (the years 2019–2021) in structure-based vaccine design.•Preview of …
The immunobiology of Nipah virus
Nipah virus (NiV) is a highly lethal zoonotic paramyxovirus that emerged in Malaysia in
1998. It is a human pathogen capable of causing severe respiratory infection and …
1998. It is a human pathogen capable of causing severe respiratory infection and …
Advancements in Nipah virus treatment: Analysis of current progress in vaccines, antivirals, and therapeutics
Nipah virus (NiV) causes severe encephalitis in humans. Three NiV strains NiV‐Malaysia
(NiVM), NiV Bangladesh (NiVB), and NiV India (NiVI reported in 2019) have been circulating …
(NiVM), NiV Bangladesh (NiVB), and NiV India (NiVI reported in 2019) have been circulating …
Both chimpanzee adenovirus-vectored and DNA vaccines induced long-term immunity against Nipah virus infection
M Lu, Y Yao, X Zhang, H Liu, G Gao, Y Peng, M Chen… - npj Vaccines, 2023 - nature.com
Nipah virus (NiV) is a highly lethal zoonotic paramyxovirus that poses a severe threat to
humans due to its high morbidity and the lack of viable countermeasures. Vaccines are the …
humans due to its high morbidity and the lack of viable countermeasures. Vaccines are the …
mRNA-based modalities for infectious disease management
The novel coronavirus disease 2019 (COVID-19) is still rampant all over the world, causing
incalculable losses to the world. Major pharmaceutical organizations around the globe are …
incalculable losses to the world. Major pharmaceutical organizations around the globe are …