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Semaphorins in adult nervous system plasticity and disease
D Carulli, F De Winter, J Verhaagen - Frontiers in synaptic …, 2021 - frontiersin.org
Semaphorins, originally discovered as guidance cues for develo** axons, are involved in
many processes that shape the nervous system during development, from neuronal …
many processes that shape the nervous system during development, from neuronal …
Kindling and status epilepticus models of epilepsy: rewiring the brain
This review focuses on the remodeling of brain circuitry associated with epilepsy, particularly
in excitatory glutamate and inhibitory GABA systems, including alterations in synaptic …
in excitatory glutamate and inhibitory GABA systems, including alterations in synaptic …
Axon guidance proteins in neurological disorders
Many neurological disorders are characterised by structural changes in neuronal
connections, ranging from presymptomatic synaptic changes to the loss or rewiring of entire …
connections, ranging from presymptomatic synaptic changes to the loss or rewiring of entire …
Guidance molecules in synapse formation and plasticity
A major goal of modern neuroscience research is to understand the cellular and molecular
processes that control the formation, function, and remodeling of chemical synapses. In this …
processes that control the formation, function, and remodeling of chemical synapses. In this …
Molecular signaling mechanisms underlying epileptogenesis
JO McNamara, YZ Huang, AS Leonard - Science's STKE, 2006 - science.org
Epilepsy, a disorder of recurrent seizures, is a common and frequently devastating
neurological condition. Available therapy is only symptomatic and often ineffective …
neurological condition. Available therapy is only symptomatic and often ineffective …
Semaphorin function in neural plasticity and disease
The semaphorins, originally discovered as evolutionarily conserved steering molecules for
develo** axons, also influence neuronal structure and function in the early postnatal and …
develo** axons, also influence neuronal structure and function in the early postnatal and …
Semaphorin 3F is critical for development of limbic system circuitry and is required in neurons for selective CNS axon guidance events
Little is known about the role of class 3 semaphorins in the development of CNS circuitry.
Several class 3 semaphorins, including semaphorin 3F (Sema3F) bind to the receptor …
Several class 3 semaphorins, including semaphorin 3F (Sema3F) bind to the receptor …
Involvement of cortical fast-spiking parvalbumin-positive basket cells in epilepsy
GABAergic interneurons of the parvalbumin-positive fast-spiking basket cells subtype (PV
INs) are important regulators of cortical network excitability and of gamma oscillations …
INs) are important regulators of cortical network excitability and of gamma oscillations …
Secreted semaphorins modulate synaptic transmission in the adult hippocampus
Modulation of synaptic activity is critical for neural circuit function and behavior. The
semaphorins are a large, phylogenetically conserved protein family with important roles in …
semaphorins are a large, phylogenetically conserved protein family with important roles in …
Role of semaphorins in the adult nervous system
In the develo** nervous system, extending axons are directed towards their appropriate
targets by a myriad of attractive and repulsive guidance cues. Work in the past decade has …
targets by a myriad of attractive and repulsive guidance cues. Work in the past decade has …