Pyrrole: a resourceful small molecule in key medicinal hetero-aromatics

V Bhardwaj, D Gumber, V Abbot, S Dhiman, P Sharma - Rsc Advances, 2015 - pubs.rsc.org
Pyrrole is widely known as a biologically active scaffold which possesses a diverse nature of
activities. The combination of different pharmacophores in a pyrrole ring system has led to …

Cross‐Coupling of Heteroarenes by C H Functionalization: Recent Progress towards Direct Arylation and Heteroarylation Reactions Involving Heteroarenes …

R Rossi, F Bellina, M Lessi… - Advanced Synthesis & …, 2014 - Wiley Online Library
In recent years, transition metal‐catalyzed direct (hetero) arylation reactions of heteroarenes
with (hetero) aryl halides and pseudohalides have received significant attention as eco …

Chiral 1, 1-diaryl compounds as important pharmacophores

D Ameen, TJ Snape - MedChemComm, 2013 - pubs.rsc.org
Compounds containing a 1, 1-diaryl motif are numerous, and compounds of this type have
found use as catalysts and molecular building blocks, however, this review focusses solely …

Isocyanide-based multicomponent reactions in water: Advanced green tools for the synthesis of heterocyclic compounds

T Nasiriani, S Javanbakht, MT Nazeri, H Farhid… - Topics in Current …, 2022 - Springer
Reaction rate acceleration using green methods is an intriguing area of research for
chemists. In this regard, water as a “green solvent” plays a crucial role in the acceleration of …

Synthesis and biological activity of vicinal diaryl-substituted 1H-imidazoles

F Bellina, S Cauteruccio, R Rossi - Tetrahedron, 2007 - Elsevier
1. Introduction....................................................................... 4572 2. Synthesis of vicinal diaryl-
substituted 1H-imidazoles..................................... 4572 2.1. Synthesis of 1, 2-diaryl-1H …

[HTML][HTML] Green synthesis, characterization and catalytic activity of 4-nitrophenol reduction and formation of benzimidazoles using bentonite supported zero valent iron …

K Sravanthi, D Ayodhya, PY Swamy - Materials Science for Energy …, 2019 - Elsevier
In this work, we report the green synthesis and characterization of a green catalyst by the
immobilization of zero-valent iron nanoparticles (ZVIN) on the surface of bentonite clay using …

Synthesis of polysubstituted pyrroles via isocyanide-based multicomponent reactions as an efficient synthesis tool

MT Nazeri, A Shaabani - New Journal of Chemistry, 2021 - pubs.rsc.org
Pyrroles are among the most privileged and influential small N-heterocycles at the core of
many commercial drugs, biological composition, natural compounds, agrochemicals, and …

A comprehensive review of N-heterocycles as cytotoxic agents

D Kumar, S Kumar Jain - Current Medicinal Chemistry, 2016 - ingentaconnect.com
Scientific community is striving to understand the role of heterocycles and fused
heterocycles in drug discovery programme due to its impact on multi-drug resistance (MDR) …

Imidazole and Azo‐Based Schiff Bases Ligands as Highly Active Antifungal and Antioxidant Components

S Slassi, A Fix-Tailler, G Larcher, A Amine… - Heteroatom …, 2019 - Wiley Online Library
We describe, herein, the synthesis, full characterization, and optical properties of four
different ligands L1-L4 which associate an azo group, an imidazole unit, and a Schiff base …

[BOOK][B] Chemistry of pyrroles

BA Trofimov, IM Al'bina, EY Schmidt, LN Sobenina - 2014 - books.google.com
During the last 30 years, knowledge of the essential role that pyrrole structures play in the
chemistry of living organisms, drug design, and the development of advanced materials has …