Breast cancer is the most common cancer and the deadliest among women worldwide.
Estrogen signaling is closely associated with hormone-dependent breast cancer (estrogen …

Background: Sex dimorphism strongly impacts tumor biology, with most cancers having a
male predominance. Uniquely, thyroid cancer (TC) is the only nonreproductive cancer with …

BACKGROUND Estrogens regulate disparate female physiological processes, thus
ensuring reproduction. Altered estrogen levels and signaling have been associated with …

Estradiol (E2) is a major hormone controlling women fertility, in particular folliculogenesis.
This steroid, which is locally produced by granulosa cells (GC) within ovarian follicles …

Disruption of intestinal homeostasis is an important event in the development of
inflammatory bowel disease (IBD), and genistein (GEN) is a candidate medicine to prevent …

It is known that estrogen stimulates growth and inhibits apoptosis through estrogen receptor
(ER)-mediated mechanisms in many cancer cell types. Interestingly, there is strong evidence …

Chronic arsenic exposure causes skin cancer, although the underlying molecular
mechanisms are not well defined. Altered microRNA and mRNA expression likely play a …

Telomeres are part of chromatin structures containing repeated DNA sequences, which
function as protective caps at the ends of chromosomes and prevent DNA degradation and …

Epidemiological evidence supports an association between cow's milk consumption and the
risk of diffuse large B-cell lymphoma (DLBCL), the most common non-Hodgkin lymphoma …

Breast cancer is the most frequently diagnosed cancer and the leading cause of death by
cancer among women worldwide. The prognosis of the disease and patients' response to …