Overview of the 2022 WHO classification of thyroid neoplasms

ZW Baloch, SL Asa, JA Barletta, RA Ghossein… - Endocrine …, 2022‏ - Springer
This review summarizes the changes in the 5th edition of the WHO Classification of
Endocrine and Neuroendocrine Tumors that relate to the thyroid gland. The new …

Pathogenesis of cancers derived from thyroid follicular cells

JA Fagin, GP Krishnamoorthy, I Landa - Nature reviews Cancer, 2023‏ - nature.com
The genomic simplicity of differentiated cancers derived from thyroid follicular cells offers
unique insights into how oncogenic drivers impact tumour phenotype. Essentially, the main …

[PDF][PDF] Guidelines for the management of thyroid cancer.

P Perros, K Boelaert, S Colley, C Evans… - Clinical …, 2014‏ - rouxgroup.org.uk
Guidelines for the management of thyroid cancer Page 1 CLINICAL ENDOCRINOLOGY
VOLUME 81 SUPPLEMENT 1 JULY 2014 THE CLINICAL JOURNAL OF THE SOCIETY FOR …

Mitochondrial dysfunction: a novel potential driver of epithelial-to-mesenchymal transition in cancer

F Guerra, N Guaragnella, AA Arbini, C Bucci… - Frontiers in …, 2017‏ - frontiersin.org
Epithelial-to-mesenchymal transition (EMT) allows epithelial cancer cells to assume
mesenchymal features, endowing them with enhanced motility and invasiveness, thus …

Clinical and molecular features of Hürthle cell carcinoma of the thyroid

AM Chindris, JD Casler, VJ Bernet… - The Journal of …, 2015‏ - academic.oup.com
Context: Hürthle cell cancer (HCC) of the thyroid remains the subject of controversy with
respect to natural course, treatment, and follow-up. Objective: The objective of the study was …

Real-world performance of the Afirma Genomic Sequencing Classifier (GSC)—a meta-analysis

CE Nasr, M Andrioli, M Endo, RM Harrell… - The Journal of …, 2023‏ - academic.oup.com
Abstract Context The Afirma® GSC aids in risk stratifying indeterminate thyroid nodule
cytology (ITN). The 2018 GSC validation study (VS) reported a sensitivity (SN) of 91 …

Molecular alterations and comprehensive clinical management of oncocytic thyroid carcinoma: a review and multidisciplinary 2023 update

LA Bischoff, I Ganly, L Fugazzola… - … –Head & Neck …, 2024‏ - jamanetwork.com
Importance Oncocytic (Hürthle cell) thyroid carcinoma is a follicular cell-derived neoplasm
that accounts for approximately 5% of all thyroid cancers. Until recently, it was categorized …

[HTML][HTML] Thyroid Hürthle cell carcinoma: clinical, pathological, and molecular features

S Kure, R Ohashi - Cancers, 2020‏ - mdpi.com
Simple Summary Hürthle cell carcinoma (HCC) represents 3–4% of thyroid carcinoma
cases. It is characterized by its large, granular and eosinophilic cytoplasm, due to an …

Pathology of endocrine tumors update: World Health Organization new classification 2017—other thyroid tumors

AK Lam - AJSP: Reviews & Reports, 2017‏ - journals.lww.com
The data on nonmedullary thyroid tumors in the fourth edition of the World Health
Organization classification of endocrine tumors contain significant revisions. The tumors …

PET/CT in the management of thyroid cancers

C Marcus, PW Whitworth, DS Surasi, SI Pai… - American Journal of …, 2014‏ - ajronline.org
OBJECTIVE. Thyroid cancer is the most common endocrine cancer. This review evaluates
the established use of 18F-FDG PET/CT in papillary, follicular, Hürthle cell, anaplastic, and …