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Phage diversity, genomics and phylogeny
Recent advances in viral metagenomics have enabled the rapid discovery of an
unprecedented catalogue of phages in numerous environments, from the human gut to the …
unprecedented catalogue of phages in numerous environments, from the human gut to the …
Phage puppet masters of the marine microbial realm
Viruses numerically dominate our oceans; however, we have only just begun to document
the diversity, host range and infection dynamics of marine viruses, as well as the subsequent …
the diversity, host range and infection dynamics of marine viruses, as well as the subsequent …
Viral community-wide auxiliary metabolic genes differ by lifestyles, habitats, and hosts
Background Viral-encoded auxiliary metabolic genes (AMGs) are important toolkits for
modulating their hosts' metabolisms and the microbial-driven biogeochemical cycles …
modulating their hosts' metabolisms and the microbial-driven biogeochemical cycles …
Biogeographic patterns and drivers of soil viromes
Viruses are crucial in sha** soil microbial functions and ecosystems. However, studies on
soil viromes have been limited in both spatial scale and biome coverage. Here we present a …
soil viromes have been limited in both spatial scale and biome coverage. Here we present a …
Revisiting the rules of life for viruses of microorganisms
Viruses that infect microbial hosts have traditionally been studied in laboratory settings with
a focus on either obligate lysis or persistent lysogeny. In the environment, these infection …
a focus on either obligate lysis or persistent lysogeny. In the environment, these infection …
Deep sea sediments associated with cold seeps are a subsurface reservoir of viral diversity
In marine ecosystems, viruses exert control on the composition and metabolism of microbial
communities, influencing overall biogeochemical cycling. Deep sea sediments associated …
communities, influencing overall biogeochemical cycling. Deep sea sediments associated …
Phage-specific metabolic reprogramming of virocells
Ocean viruses are abundant and infect 20–40% of surface microbes. Infected cells, termed
virocells, are thus a predominant microbial state. Yet, virocells and their ecosystem impacts …
virocells, are thus a predominant microbial state. Yet, virocells and their ecosystem impacts …
Global overview and major challenges of host prediction methods for uncultivated phages
Highlights•Global phage diversity is now primarily explored through cultivation-independent
metagenomics.•Metagenome-derived phages are typically linked to their host (s) via in silico …
metagenomics.•Metagenome-derived phages are typically linked to their host (s) via in silico …
Expanding standards in viromics: in silico evaluation of dsDNA viral genome identification, classification, and auxiliary metabolic gene curation
Background Viruses influence global patterns of microbial diversity and nutrient cycles.
Though viral metagenomics (viromics), specifically targeting dsDNA viruses, has been …
Though viral metagenomics (viromics), specifically targeting dsDNA viruses, has been …
Studying the gut virome in the metagenomic era: challenges and perspectives
The human gut harbors a complex ecosystem of microorganisms, including bacteria and
viruses. With the rise of next-generation sequencing technologies, we have seen a quantum …
viruses. With the rise of next-generation sequencing technologies, we have seen a quantum …