Mental disorders represent common brain diseases characterized by substantial
impairments of social and cognitive functions. The neurobiological causes and mechanisms …

Myelination of axons provides the structural basis for rapid saltatory impulse propagation
along vertebrate fiber tracts, a well-established neurophysiological concept. However …

Understanding the organizational logic of neural circuits requires deciphering the biological
basis of neuronal diversity and identity, but there is no consensus on how neuron types …

Highlights•Quercetin significantly ameliorated the phenotypes and decreased the ROS
production levels in DPN rats.•Quercetin was firstly found to modulate gut microbiota in DPN …

The efficient propagation of action potentials along nervous fibers is necessary for animals
to interact with the environment with timeliness and precision. Myelination of axons is an …

Along myelinated axons, Shaker-type potassium channels (Kv1) accumulate at high density
in the juxtaparanodal region, directly adjacent to the paranodal axon–glia junctions that …

Contactins (Cntns) are a six-member subgroup of the immunoglobulin cell adhesion
molecule superfamily (IgCAMs) with pronounced brain expression and function. Recent …

Genome-wide association studies and copy number variation analyses have linked
contactin associated protein 2 (Caspr2, gene name Cntnap2) with autism spectrum disorder …

Over the past three decades, genetic manipulations in mice have been used in
neuroscience as a major approach to investigate the in vivo function of genes and their …

This review article focuses on the Contactin (CNTN) subset of the Immunoglobulin
supergene family (IgC2/FNIII molecules), whose components share structural properties (the …