Psoriasis is the result of uncontrolled keratinocyte proliferation, and its pathogenesis
involves the dysregulation of the immune system. The interplay among cytokines released …

Curcumin (CUR) is a polyphenol extracted from the rhizome of Curcuma longa that
possesses potent anti-inflammatory and antioxidant potential. Despite CUR's numerous …

Background The systemic immune-inflammation index (SII), as measured by lymphocyte,
neutrophil and platelet counts in peripheral blood, is regarded as a favorable indicator of …

Janus kinase (JAK) inhibitors are novel treatment approaches for psoriasis. However, there
is no direct comparison of JAK inhibitors in plaque psoriasis. In order to compare the efficacy …

Psoriasis is a common chronic inflammatory skin disease driven by the aberrant activation of
dendritic cells (DCs) and T cells, ultimately leading to increased production of cytokines …

The study of psoriasis has yielded fundamental new insights into immunologic regulation
and innovative therapies in a way that few other diseases have. In this review, we …

An association of melatonin levels with age disease initiation of autoimmune diseases and
pineal calcification was reported while an inverse association between melatonin levels and …

Psoriasis is a chronic autoimmune inflammatory disease characterized by erroneous
metabolism of keratinocytes. The development of psoriasis is closely related to abnormal …

Psoriasis is a deleterious auto-immune disorder which seriously harms the patients physical
and mental health. CD44 are found to be over-expressed on psoriatic lesions which are …

The management of patients affected by moderate-to-severe psoriasis may be challenging,
in particular in patients with serious infectious diseases [tuberculosis (TB), hepatitis B and C …