[HTML][HTML] Long-acting transdermal drug delivery formulations: Current developments and innovative pharmaceutical approaches

T Karve, A Dandekar, V Agrahari, MM Peet… - Advanced Drug Delivery …, 2024‏ - Elsevier
Transdermal administration remains an active research and development area as an
alternative route for long-acting drug delivery. It avoids major drawbacks of conventional oral …

Advances in lipid-based colloid systems as drug carrier for topic delivery

Y Zhai, G Zhai - Journal of controlled release, 2014‏ - Elsevier
Introduction Based on the advantages of transcutaneous delivery and the application status
of nanocarriers in transcutaneous delivery, this paper critically reviews the correlation of …

Development of paroxetine loaded nanotransferosomal gel for intranasal delivery with enhanced antidepressant activity in rats

A Tahir, S Aslam, S Sohail, F ud Din, AH Alamri… - Colloids and Surfaces B …, 2025‏ - Elsevier
The aim of this study was to develop paroxetine (PXT) loaded nanotransferosomal gel (PXT-
NTFG) for intranasal brain delivery. The process involved fabricating PXT-NTFs (paroxetine …

Vesicular system: Versatile carrier for transdermal delivery of bioactives

D Singh, M Pradhan, M Nag… - … cells, nanomedicine, and …, 2015‏ - Taylor & Francis
The transdermal route of drug delivery has gained immense interest for pharmaceutical
researchers. The major hurdle for diffusion of drugs and bioactives through transdermal …

Recent options and techniques to assess improved bioavailability: in vitro and ex vivo methods

L Józsa, D Nemes, Á Pető, D Kósa, R Révész… - Pharmaceutics, 2023‏ - mdpi.com
Bioavailability assessment in the development phase of a drug product is vital to reveal the
disadvantageous properties of the substance and the possible technological interventions …

Maximizing the therapeutic efficacy of imatinib mesylate–loaded niosomes on human colon adenocarcinoma using Box-Behnken design

MA Kassem, HS El-Sawy, FI Abd-Allah… - Journal of …, 2017‏ - Elsevier
This research purposed to formulate an optimized imatinib mesylate (IM)–loaded niosomes
to improve its chemotherapeutic efficacy. The influence of 3 formulation factors on niosomal …

Natamycin niosomes as a promising ocular nanosized delivery system with ketorolac tromethamine for dual effects for treatment of candida rabbit keratitis; in vitro/in …

MA El-Nabarawi, RT Abd El Rehem… - Drug development …, 2019‏ - Taylor & Francis
Objectives: This study was aimed to develop dual-purpose natamycin (NAT)-loaded
niosomes in ketorolac tromethamine (KT) gels topical ocular drug delivery system to improve …

Recent advances in nanocarrier-loaded gels: Which drug delivery technologies against which diseases?

M Pitorre, H Gondé, C Haury, M Messous… - Journal of Controlled …, 2017‏ - Elsevier
The combination of pharmaceutical technologies can be a wise choice for develo**
innovative therapeutic strategies. The association of nanocarriers and gels provides new …

Optimized nano-transfersomal films for enhanced sildenafil citrate transdermal delivery: ex vivo and in vivo evaluation

SM Badr-Eldin, OAA Ahmed - Drug design, development and …, 2016‏ - Taylor & Francis
Sildenafil citrate (SLD) is a selective cyclic guanosine monophosphate-specific
phosphodiesterase type 5 inhibitor used for the oral treatment of erectile dysfunction and …