[HTML][HTML] A machine learning method for real-time numerical simulations of cardiac electromechanics

F Regazzoni, M Salvador, L Dedè… - Computer methods in …, 2022 - Elsevier
We propose a machine learning-based method to build a system of differential equations
that approximates the dynamics of 3D electromechanical models for the human heart …

[HTML][HTML] Accelerating the convergence to a limit cycle in 3D cardiac electromechanical simulations through a data-driven 0D emulator

F Regazzoni, A Quarteroni - Computers in Biology and Medicine, 2021 - Elsevier
The results of numerical simulations of cardiac electromechanics are typically characterized
by a long transient before reaching a periodic solution known as limit cycle. This yields a …

Partitioned and monolithic algorithms for the numerical solution of cardiac fluid-structure interaction

M Bucelli, L Dede, A Quarteroni… - Communications in …, 2023 - re.public.polimi.it
We review and compare different fluid-structure interaction (FSI) numerical methods in the
context of heart modeling, aiming at assessing their computational efficiency for cardiac …

Efficient approximation of cardiac mechanics through reduced‐order modeling with deep learning‐based operator approximation

L Cicci, S Fresca, A Manzoni… - International Journal for …, 2024 - Wiley Online Library
Reducing the computational time required by high‐fidelity, full‐order models (FOMs) for the
solution of problems in cardiac mechanics is crucial to allow the translation of patient …

Modeling the cardiac electromechanical function: A mathematical journey

A Quarteroni, L Dedè, F Regazzoni - Bulletin of the American Mathematical …, 2022 - ams.org
In this paper we introduce the electromechanical mathematical model of the human heart.
After deriving it from physical first principles, we discuss its mathematical properties and the …

A reduced 3D-0D FSI model of the aortic valve including leaflets curvature

I Fumagalli - arxiv preprint arxiv:2106.00571, 2021 - arxiv.org
In the present work, we propose a novel lumped-parameter model for the description of the
aortic valve dynamics, including elastic effects associated to the leaflets' curvature. The …

[PDF][PDF] Stabilization of staggered time discretization schemes for 0D-3D fluid-structure interaction problems

F Regazzoni - MOX report, 2022 - mate.polimi.it
In this paper we analyze the numerical oscillations affecting time-staggered schemes for 0D-
3D fluid-structure interaction (FSI) problems, which arise eg in the field of cardiovascular …

Mathematical and numerical models for the cardiac electromechanical function

L Dede, A Quarteroni, F Regazzoni - Rendiconti Lincei, 2021 - ems.press
This paper deals with the mathematical model that describes the function of the human
heart. More specifically, it addresses the equations that express the electromechanical …

Mathematical and numerical modeling of cardiac fiber generation and electromechanical function: towards a realistic simulation of the whole heart

R Piersanti - 2021 - politesi.polimi.it
Cardiovascular diseases are the primary cause of mortality worldwide, affecting millions of
people every year. Although advancements in medical practice are continuously improving …

Efficient reduced order modeling for nonlinear parameterized problems in elastodynamics: application to cardiac mechanics

L Cicci - 2021 - politesi.polimi.it
In this Thesis we propose new computationally efficient solutions to nonlinear,
parameterized time-dependent problems by means of reduced order models (ROMs). More …