Evidence implicating non-dioxin-like congeners as the key mediators of polychlorinated biphenyl (PCB) developmental neurotoxicity

C Klocke, PJ Lein - International journal of molecular sciences, 2020 - mdpi.com
Despite being banned from production for decades, polychlorinated biphenyls (PCBs)
continue to pose a significant risk to human health. This is due to not only the continued …

Using zebrafish to model autism spectrum disorder: a comparison of ASD risk genes between zebrafish and their mammalian counterparts

V Rea, TJ Van Raay - Frontiers in molecular neuroscience, 2020 - frontiersin.org
Autism spectrum disorders (ASDs) are a highly variable and complex set of neurological
disorders that alter neurodevelopment and cognitive function, which usually presents with …

[HTML][HTML] Polychlorinated biphenyls (PCBs): risk factors for autism spectrum disorder?

HK Panesar, CL Kennedy, KP Keil Stietz, PJ Lein - Toxics, 2020 - mdpi.com
Autism spectrum disorder (ASD) includes a group of multifactorial neurodevelopmental
disorders defined clinically by core deficits in social reciprocity and communication …

Executive function skills are linked to restricted and repetitive behaviors: Three correlational meta analyses

RK Iversen, C Lewis - Autism Research, 2021 - Wiley Online Library
There is a consensus on the centrality of restricted and repetitive behaviors (RRBs) in the
diagnosis of Autism Spectrum Disorder (ASD), yet the origins of these behaviors are still …

Parenting challenges in families of children with a diagnosis of autism spectrum disorder: A qualitative research study in Istanbul

M Rfat, O Koçak, B Uzun - Global Social Welfare, 2023 - Springer
Introduction This qualitative research study examines problems experienced by families with
children who have received a diagnosis of autism spectrum disorder (ASD) living in Turkey …

[HTML][HTML] Inhibitory dysfunction and social processing difficulties in autism: A comprehensive narrative review

NF Parrella, AT Hill, LM Dipnall, YJ Loke… - Journal of Psychiatric …, 2024 - Elsevier
The primary inhibitory neurotransmitter γ-aminobutyric acid (GABA) has a prominent role in
regulating neural development and function, with disruption to GABAergic signalling linked …

Loss of Cntnap2 in the Rat Causes Autism‐Related Alterations in Social Interactions, Stereotypic Behavior, and Sensory Processing

KE Scott, K Kazazian, RS Mann, D Möhrle… - Autism …, 2020 - Wiley Online Library
Autism spectrum disorder (ASD) is characterized by social interaction and communication
impairments, as well as restrictive/repetitive patterns of behavior, interests or activities, which …

Synaptic dysfunction connects autism spectrum disorder and sleep disturbances: A perspective from studies in model organisms

F Doldur-Balli, T Imamura, OJ Veatch, NN Gong… - Sleep medicine …, 2022 - Elsevier
Sleep disturbances (SD) accompany many neurodevelopmental disorders, suggesting SD is
a transdiagnostic process that can account for behavioral deficits and influence underlying …

Pathophysiological studies of monoaminergic neurotransmission systems in valproic acid-induced model of autism spectrum disorder

HY Kuo, FC Liu - Biomedicines, 2022 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with complex etiology.
The core syndromes of ASD are deficits in social communication and self-restricted interests …

A systematic review of brainstem contributions to autism spectrum disorder

A Seif, C Shea, S Schmid… - Frontiers in Integrative …, 2021 - frontiersin.org
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that affects one in 66
children in Canada. The contributions of changes in the cortex and cerebellum to autism …