Antimicrobial peptides: Structure, mechanism, and modification

N Chen, C Jiang - European Journal of Medicinal Chemistry, 2023 - Elsevier
From the 1940s to the 1960s, the discovery of antibiotics held substantial promise for the
treatment of bacterial infection, and it was also widely used in food, agriculture, and other …

Antibacterial carbon dots: mechanisms, design, and applications

WB Zhao, KK Liu, Y Wang, FK Li, R Guo… - Advanced …, 2023 - Wiley Online Library
The increase in antibiotic resistance promotes the situation of develo** new antibiotics at
the forefront, while the development of non‐antibiotic pharmaceuticals is equally significant …

Antimicrobial peptides: A new hope in biomedical and pharmaceutical fields

A Moretta, C Scieuzo, AM Petrone, R Salvia… - Frontiers in cellular …, 2021 - frontiersin.org
Antibiotics are essential drugs used to treat pathogenic bacteria, but their prolonged use
contributes to the development and spread of drug-resistant microorganisms. Antibiotic …

The multifaceted nature of antimicrobial peptides: Current synthetic chemistry approaches and future directions

BH Gan, J Gaynord, SM Rowe, T Deingruber… - Chemical Society …, 2021 - pubs.rsc.org
Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …

Antimicrobial peptides: classification, design, application and research progress in multiple fields

Y Huan, Q Kong, H Mou, H Yi - Frontiers in microbiology, 2020 - frontiersin.org
Antimicrobial peptides (AMPs) are a class of small peptides that widely exist in nature and
they are an important part of the innate immune system of different organisms. AMPs have a …

Chemically modified and conjugated antimicrobial peptides against superbugs

W Li, F Separovic, NM O'Brien-Simpson… - Chemical Society …, 2021 - pubs.rsc.org
Antimicrobial resistance (AMR) is one of the greatest threats to human health that, by 2050,
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …

Quaternary ammonium salts: insights into synthesis and new directions in antibacterial applications

Z Zhou, S Zhou, X Zhang, S Zeng, Y Xu… - Bioconjugate …, 2023 - ACS Publications
The overuse of antibiotics has led to the emergence of a large number of antibiotic-resistant
genes in bacteria, and increasing evidence indicates that a fungicide with an antibacterial …

Potential causes of spread of antimicrobial resistance and preventive measures in one health perspective-a review

H Endale, M Mathewos, D Abdeta - Infection and drug resistance, 2023 - Taylor & Francis
Antimicrobial resistance, referring to microorganisms' capability to subsist and proliferate
even when there are antimicrobials is a foremost threat to public health globally. The …

Machine learning for antimicrobial peptide identification and design

F Wan, F Wong, JJ Collins… - Nature Reviews …, 2024 - nature.com
Artificial intelligence (AI) and machine learning (ML) models are being deployed in many
domains of society and have recently reached the field of drug discovery. Given the …

Antimicrobial drug resistance in poultry production: Current status and innovative strategies for bacterial control

R Abreu, T Semedo-Lemsaddek, E Cunha, L Tavares… - Microorganisms, 2023 - mdpi.com
The world population's significant increase has promoted a higher consumption of poultry
products, which must meet the specified demand while maintaining their quality and safety. It …