Chiral fungicide penconazole: Absolute configuration, bioactivity, toxicity, and stereoselective degradation in apples
Y Li, J Nie, J Zhang, G Xu, H Zhang, M Liu… - Science of the Total …, 2022 - Elsevier
Traditional evaluation of chiral pesticides can lead to inaccurate results, as their
enantiomers may show different properties. Penconazole, a chiral triazole fungicide with two …
enantiomers may show different properties. Penconazole, a chiral triazole fungicide with two …
Biological effects of bis-hydrazone compounds bearing isovanillin moiety on the aldose reductase
Abstract Aldose reductase (ALR2), one of the metabolically important enzymes, catalyzes
the formation of sorbitol from glucose in the polyol pathway. ALR2 inhibition is required to …
the formation of sorbitol from glucose in the polyol pathway. ALR2 inhibition is required to …
Probing 4-(diethylamino)-salicylaldehyde-based thiosemicarbazones as multi-target directed ligands against cholinesterases, carbonic anhydrases and α-glycosidase …
With the fading of 'one drug-one target'approach, Multi-Target-Directed Ligands (MTDL) has
become a central idea in modern Medicinal Chemistry. The present study aimed to design …
become a central idea in modern Medicinal Chemistry. The present study aimed to design …
A novel series of thiosemicarbazone hybrid scaffolds: Design, synthesis, DFT studies, metabolic enzyme inhibition properties, and molecular docking calculations
The fourteen new thiosemicarbazone derivatives of Schiff base were synthesized from the
condensation reactions of two different aldehydes (3‑hydroxy-4-methoxhybenzaldehyde and …
condensation reactions of two different aldehydes (3‑hydroxy-4-methoxhybenzaldehyde and …
Recent advances in biotechnology applications of bacteriocin-selenium nanoconjugates
SMH Al-Shimmary, AN Al-Thwani - Inorganic Chemistry Communications, 2024 - Elsevier
Owing to the lack of progress in the development of antibiotics, there is a pressing need for
innovative approaches to treat microbial infections. Nanotechnology and natural peptides …
innovative approaches to treat microbial infections. Nanotechnology and natural peptides …
Novel potential metabolic enzymes inhibitor, photosensitizer and antibacterial agents based on water-soluble phthalocyanine bearing imidazole derivative
In this work, we have reported on the synthesis and characterization of water-soluble
hydrochloride forms (2a-4a) based on novel peripherally [M= metal-free (2), zinc (II)(3) …
hydrochloride forms (2a-4a) based on novel peripherally [M= metal-free (2), zinc (II)(3) …
PEPPSI type Pd (II) NHC complexes bearing chloro-/fluorobenzyl group: Synthesis, characterization, crystal structures, α-glycosidase and acetylcholinesterase …
This work reported the synthesis of a new PEPPSI (Pyridine Enhanced Precatalyst
Preparation, Stabilization and Initiation) type Pd (II) N-heterocyclic carbene (NHC) …
Preparation, Stabilization and Initiation) type Pd (II) N-heterocyclic carbene (NHC) …
Tail-approach based design, synthesis, and cytotoxic evaluation of novel disubstituted and trisubstituted 1, 3-thiazole benzenesulfonamide derivatives with suggested …
A novel series of 2, 4, 5-and 2, 3, 4-trisubstituted thiazole hybrids with 1, 3, 4-
thiadiazolylbenzenesulfonamide was designed following the tail approach as possible …
thiadiazolylbenzenesulfonamide was designed following the tail approach as possible …
Hybrid quinoline-thiosemicarbazone therapeutics as a new treatment opportunity for Alzheimer's disease‒synthesis, in vitro cholinesterase inhibitory potential and …
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the leading
cause of dementia worldwide. The limited pharmacological approaches based on …
cause of dementia worldwide. The limited pharmacological approaches based on …
Highly selective radical isothiocyano-chalcogenization of alkenes with NH 4 SCN in water
C Xu, Z He, X Kang, Q Zeng - Green Chemistry, 2021 - pubs.rsc.org
In the presence of catalytic amounts of molecular iodine and stoichiometric potassium
persulfate, a green, highly chemoselective, regioselective and cis-selective radical …
persulfate, a green, highly chemoselective, regioselective and cis-selective radical …