Targeting the PI3K/AKT/mTOR and RAF/MEK/ERK pathways for cancer therapy

Q Li, Z Li, T Luo, H Shi - Molecular biomedicine, 2022 - Springer
Abstract The PI3K/AKT/mTOR and RAF/MEK/ERK pathways are commonly activated by
mutations and chromosomal translocation in vital targets. The PI3K/AKT/mTOR signaling …

[HTML][HTML] Phytochemistry and pharmacological compounds present in scent leaf: A review

GI Edo, PO Samuel, S Ossai, SC Nwachukwu… - Food Chemistry …, 2023 - Elsevier
This article explores the phytochemistry and pharmacology of scent leaf, also known as
African basil or Ocimum gratissimum. Scent leaf has been traditionally used in herbal …

Natural compounds-based nanomedicines for cancer treatment: Future directions and challenges

T Andreani, R Cheng, K Elbadri, C Ferro… - Drug Delivery and …, 2024 - Springer
Several efforts have been extensively accomplished for the amelioration of the cancer
treatments using different types of new drugs and less invasives therapies in comparison …

Herbal therapies for cancer treatment: A review of phytotherapeutic efficacy

A Jenča, DK Mills, H Ghasemi, E Saberian… - … : Targets and Therapy, 2024 - Taylor & Francis
Natural products have proven to be promising anti-cancer agents due to their diverse
chemical structures and bioactivity. This review examines their central role in cancer …

[HTML][HTML] The potential of herbal drugs to treat heart failure: The roles of Sirt1/AMPK

T Zhang, L Xu, X Guo, H Tao, Y Liu, X Liu… - Journal of …, 2024 - Elsevier
Heart failure (HF) is a highly morbid syndrome that seriously affects the physical and mental
health of patients and generates an enormous socio-economic burden. In addition to cardiac …

Natural compounds and glutathione: Beyond mere antioxidants

C Di Giacomo, GA Malfa, B Tomasello, S Bianchi… - Antioxidants, 2023 - mdpi.com
The tripeptide glutathione plays important roles in many cell processes, including
differentiation, proliferation, and apoptosis; in fact, disorders in glutathione homeostasis are …

Anticancer effect of terpenes: focus on malignant melanoma

P Wróblewska-Łuczka, J Cabaj, J Bargieł… - Pharmacological …, 2023 - Springer
Melanoma is a highly aggressive and life-threatening form of skin cancer that accounts for a
significant proportion of cancer-related deaths worldwide. Although conventional cancer …

[HTML][HTML] Evaluation of the Interaction between Carvacrol and Thymol, Major Compounds of Ptychotis verticillata Essential Oil: Antioxidant, Anti-Inflammatory and …

M Taibi, A Elbouzidi, M Haddou, A Baraich, D Ou-Yahia… - Life, 2024 - mdpi.com
The objective of this study was to evaluate the antioxidant, anti-inflammatory, and anticancer
properties of thymol, carvacrol, and their equimolar mixture. Antioxidant activities were …

Advanced application of nanotechnology in active constituents of Traditional Chinese Medicines

C Qiu, JZ Zhang, B Wu, CC Xu, HH Pang… - Journal of …, 2023 - Springer
Abstract Traditional Chinese Medicines (TCMs) have been used for centuries for the
treatment and management of various diseases. However, their effective delivery to targeted …

Therapeutic effects of natural products on cervical cancer: based on inflammatory pathways

ZW Zhou, HZ Long, SG Xu, FJ Li, Y Cheng… - Frontiers in …, 2022 - frontiersin.org
Inflammation is a protective response of the body to an irritant. When an inflammatory
response occurs, immune cells are recruited to the injury, eliminating the irritation. The …