Targeting the PI3K/AKT/mTOR and RAF/MEK/ERK pathways for cancer therapy
Q Li, Z Li, T Luo, H Shi - Molecular biomedicine, 2022 - Springer
Abstract The PI3K/AKT/mTOR and RAF/MEK/ERK pathways are commonly activated by
mutations and chromosomal translocation in vital targets. The PI3K/AKT/mTOR signaling …
mutations and chromosomal translocation in vital targets. The PI3K/AKT/mTOR signaling …
[HTML][HTML] Phytochemistry and pharmacological compounds present in scent leaf: A review
GI Edo, PO Samuel, S Ossai, SC Nwachukwu… - Food Chemistry …, 2023 - Elsevier
This article explores the phytochemistry and pharmacology of scent leaf, also known as
African basil or Ocimum gratissimum. Scent leaf has been traditionally used in herbal …
African basil or Ocimum gratissimum. Scent leaf has been traditionally used in herbal …
Natural compounds-based nanomedicines for cancer treatment: Future directions and challenges
T Andreani, R Cheng, K Elbadri, C Ferro… - Drug Delivery and …, 2024 - Springer
Several efforts have been extensively accomplished for the amelioration of the cancer
treatments using different types of new drugs and less invasives therapies in comparison …
treatments using different types of new drugs and less invasives therapies in comparison …
Herbal therapies for cancer treatment: A review of phytotherapeutic efficacy
Natural products have proven to be promising anti-cancer agents due to their diverse
chemical structures and bioactivity. This review examines their central role in cancer …
chemical structures and bioactivity. This review examines their central role in cancer …
[HTML][HTML] The potential of herbal drugs to treat heart failure: The roles of Sirt1/AMPK
T Zhang, L Xu, X Guo, H Tao, Y Liu, X Liu… - Journal of …, 2024 - Elsevier
Heart failure (HF) is a highly morbid syndrome that seriously affects the physical and mental
health of patients and generates an enormous socio-economic burden. In addition to cardiac …
health of patients and generates an enormous socio-economic burden. In addition to cardiac …
Natural compounds and glutathione: Beyond mere antioxidants
The tripeptide glutathione plays important roles in many cell processes, including
differentiation, proliferation, and apoptosis; in fact, disorders in glutathione homeostasis are …
differentiation, proliferation, and apoptosis; in fact, disorders in glutathione homeostasis are …
Anticancer effect of terpenes: focus on malignant melanoma
P Wróblewska-Łuczka, J Cabaj, J Bargieł… - Pharmacological …, 2023 - Springer
Melanoma is a highly aggressive and life-threatening form of skin cancer that accounts for a
significant proportion of cancer-related deaths worldwide. Although conventional cancer …
significant proportion of cancer-related deaths worldwide. Although conventional cancer …
[HTML][HTML] Evaluation of the Interaction between Carvacrol and Thymol, Major Compounds of Ptychotis verticillata Essential Oil: Antioxidant, Anti-Inflammatory and …
The objective of this study was to evaluate the antioxidant, anti-inflammatory, and anticancer
properties of thymol, carvacrol, and their equimolar mixture. Antioxidant activities were …
properties of thymol, carvacrol, and their equimolar mixture. Antioxidant activities were …
Advanced application of nanotechnology in active constituents of Traditional Chinese Medicines
C Qiu, JZ Zhang, B Wu, CC Xu, HH Pang… - Journal of …, 2023 - Springer
Abstract Traditional Chinese Medicines (TCMs) have been used for centuries for the
treatment and management of various diseases. However, their effective delivery to targeted …
treatment and management of various diseases. However, their effective delivery to targeted …
Therapeutic effects of natural products on cervical cancer: based on inflammatory pathways
ZW Zhou, HZ Long, SG Xu, FJ Li, Y Cheng… - Frontiers in …, 2022 - frontiersin.org
Inflammation is a protective response of the body to an irritant. When an inflammatory
response occurs, immune cells are recruited to the injury, eliminating the irritation. The …
response occurs, immune cells are recruited to the injury, eliminating the irritation. The …