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Neuronal circuitry for recognition memory of object and place in rodent models
Rats and mice are used for studying neuronal circuits underlying recognition memory due to
their ability to spontaneously remember the occurrence of an object, its place and an …
their ability to spontaneously remember the occurrence of an object, its place and an …
Neuronal vector coding in spatial cognition
Several types of neurons involved in spatial navigation and memory encode the distance
and direction (that is, the vector) between an agent and items in its environment. Such …
and direction (that is, the vector) between an agent and items in its environment. Such …
Acetylcholine deficiency disrupts extratelencephalic projection neurons in the prefrontal cortex in a mouse model of Alzheimer's disease
Short-term memory deficits have been associated with prefrontal cortex (PFC) dysfunction in
Alzheimer's disease (AD) and AD mouse models. Extratelencephalic projection (ET) …
Alzheimer's disease (AD) and AD mouse models. Extratelencephalic projection (ET) …
Subicular neurons encode concave and convex geometries
Animals in the natural world constantly encounter geometrically complex landscapes.
Successful navigation requires that they understand geometric features of these landscapes …
Successful navigation requires that they understand geometric features of these landscapes …
[HTML][HTML] Predictive maps in rats and humans for spatial navigation
Much of our understanding of navigation comes from the study of individual species, often
with specific tasks tailored to those species. Here, we provide a novel experimental and …
with specific tasks tailored to those species. Here, we provide a novel experimental and …
Viral vectors for neural circuit map** and recent advances in trans-synaptic anterograde tracers
Viral tracers are important tools for neuroanatomical map** and genetic payload delivery.
Genetically modified viruses allow for cell-type-specific targeting and overcome many …
Genetically modified viruses allow for cell-type-specific targeting and overcome many …
Probing neural circuit mechanisms in Alzheimer's disease using novel technologies
The study of Alzheimer's Disease (AD) has traditionally focused on neuropathological
mechanisms that has guided therapies that attenuate neuropathological features. A new …
mechanisms that has guided therapies that attenuate neuropathological features. A new …
Propagation of hippocampal ripples to the neocortex by way of a subiculum-retrosplenial pathway
Bouts of high frequency activity known as sharp wave ripples (SPW-Rs) facilitate
communication between the hippocampus and neocortex. However, the paths and …
communication between the hippocampus and neocortex. However, the paths and …
Olfactory bulb activity shapes the development of entorhinal-hippocampal coupling and associated cognitive abilities
The interplay between olfaction and higher cognitive processing has been documented in
the adult brain; however, its development is poorly understood. In mice, shortly after birth …
the adult brain; however, its development is poorly understood. In mice, shortly after birth …
[HTML][HTML] Characteristics of fMRI responses to visual stimulation in anesthetized vs. awake mice
The functional characteristics of the mouse visual system have not previously been well
explored using fMRI. In this research, we examined 9.4 T BOLD fMRI responses to visual …
explored using fMRI. In this research, we examined 9.4 T BOLD fMRI responses to visual …