Predicting esophagitis after chemoradiation therapy for non-small cell lung cancer: an individual patient data meta-analysis

DA Palma, S Senan, C Oberije, J Belderbos… - International Journal of …, 2013 - Elsevier
Purpose Concurrent chemoradiation therapy (CCRT) improves survival compared with
sequential treatment for locally advanced non-small cell lung cancer, but it increases toxicity …

Towards the interpretability of machine learning predictions for medical applications targeting personalised therapies: a cancer case survey

AJ Banegas-Luna, J Peña-García, A Iftene… - International Journal of …, 2021 - mdpi.com
Artificial Intelligence is providing astonishing results, with medicine being one of its favourite
playgrounds. Machine Learning and, in particular, Deep Neural Networks are behind this …

Machine learning algorithms for outcome prediction in (chemo) radiotherapy: An empirical comparison of classifiers

TM Deist, FJWM Dankers, G Valdes… - Medical …, 2018 - Wiley Online Library
Purpose Machine learning classification algorithms (classifiers) for prediction of treatment
response are becoming more popular in radiotherapy literature. General Machine learning …

Revisiting the dose constraints for head and neck OARs in the current era of IMRT

NP Brodin, WA Tomé - Oral oncology, 2018 - Elsevier
Head and neck cancer poses a particular challenge in radiation therapy, whilst being an
effective treatment modality it requires very high doses of radiation to provide effective …

Systematic review of normal tissue complication models relevant to standard fractionation radiation therapy of the head and neck region published after the QUANTEC …

NP Brodin, R Kabarriti, MK Garg, C Guha… - International Journal of …, 2018 - Elsevier
There has recently been an increasing interest in model-based evaluation and comparison
of different treatment options in radiation oncology studies. This is partly driven by the …

Multiple comparisons permutation test for image based data mining in radiotherapy

C Chen, M Witte, W Heemsbergen, M Herk - Radiation Oncology, 2013 - Springer
Comparing incidental dose distributions (ie images) of patients with different outcomes is a
straightforward way to explore dose-response hypotheses in radiotherapy. In this paper, we …

Multivariable normal-tissue complication modeling of acute esophageal toxicity in advanced stage non-small cell lung cancer patients treated with intensity-modulated …

R Wijsman, F Dankers, EGC Troost… - Radiotherapy and …, 2015 - Elsevier
Background and purpose The majority of normal-tissue complication probability (NTCP)
models for acute esophageal toxicity (AET) in advanced stage non-small cell lung cancer …

Generalizability assessment of head and neck cancer NTCP models based on the TRIPOD criteria

M Sharabiani, E Clementel, N Andratschke… - Radiotherapy and …, 2020 - Elsevier
This review aimed to provide an overview of the level of maturity of normal tissue
complication probability (NTCP) models for head and neck cancer (HNC) patients. A …

Dosimetric parameters associated with radiation-induced esophagitis in breast cancer patients undergoing regional nodal irradiation

A Yaney, AS Ayan, X Pan, S Jhawar, E Healy… - Radiotherapy and …, 2021 - Elsevier
Abstract Background/Purpose Rates of acute esophagitis in breast cancer patients
undergoing regional nodal irradiation (RNI) are under-reported. We set to identify …

Comparison of toxicity and outcome in advanced stage non-small cell lung cancer patients treated with intensity-modulated (chemo-) radiotherapy using IMRT or …

R Wijsman, F Dankers, EGC Troost… - Radiotherapy and …, 2017 - Elsevier
Retrospective evaluation of 188 advanced stage non-small cell lung cancer patients treated
with IMRT or VMAT revealed a limited increase of moderate to severe acute esophageal …