Depression in multiple sclerosis: Is one approach for its management enough?

CD Jones, R Motl, BM Sandroff - Multiple Sclerosis and Related Disorders, 2021 - Elsevier
Background Major depression disorder (MDD) and severe depression symptoms are highly
prevalent in multiple sclerosis (MS). Depression can worsen symptoms of MS and is …

Current perspectives on the diagnosis and management of fatigue in multiple sclerosis

O Marchesi, C Vizzino, M Filippi… - Expert Review of …, 2022 - Taylor & Francis
Introduction Fatigue is a common and debilitating symptom among multiple sclerosis (MS)
patients with a prevalence up to 81% and with a considerable impact on quality of life …

Microglial phagocytosis of neurons: diminishing neuronal loss in traumatic, infectious, inflammatory, and autoimmune CNS disorders

SF Yanuck - Frontiers in psychiatry, 2019 - frontiersin.org
Errors in neuron-microglial interaction are known to lead to microglial phagocytosis of live
neurons and excessive neuronal loss, potentially yielding poorer clinical outcomes. Factors …

Quality of life in patients with multiple sclerosis and its association with depressive symptoms and physical disability

A Ochoa-Morales, T Hernández-Mojica… - Multiple sclerosis and …, 2019 - Elsevier
Objective The aim of this work was to evaluate the quality of life of patients with multiple
sclerosis and its association with depressive symptoms and physical health. Method A total …

Fatigue in multiple sclerosis patients with different clinical phenotypes: a clinical and magnetic resonance imaging study

O Marchesi, C Vizzino, A Meani, L Conti… - European Journal of …, 2020 - Wiley Online Library
Background and purpose The prevalence of fatigue and its relation with clinical,
neuropsychological and brain magnetic resonance imaging (MRI) variables in a large cohort …

[HTML][HTML] Chronic fatigue and depression due to multiple sclerosis: Immune-inflammatory pathways, tryptophan catabolites and the gut-brain axis as possible shared …

H Ormstad, CS Simonsen, L Broch, M Maes… - Multiple sclerosis and …, 2020 - Elsevier
Abstract/summary Chronic fatigue and major depression (MDD)-like symptoms are common
manifestations of multiple sclerosis (MS), both with huge impact on quality of life. Depression …

Understanding the mechanisms of fatigue in multiple sclerosis: linking interoception, metacognition and white matter dysconnectivity

I Danciut, CL Rae, W Rashid, J Scott… - Brain …, 2024 - academic.oup.com
One of the most prominent symptoms in multiple sclerosis is pathological fatigue, often
described by sufferers as one of the most debilitating symptoms, affecting quality of life and …

Barriers to quality of life in patients with multiple sclerosis: a qualitative study

Z Hosseini, A Homayuni, M Etemadifar - BMC neurology, 2022 - Springer
Background Multiple sclerosis (MS) is a chronic progressive disease of the central nervous
system that affects the patients' quality of life. This research was conducted with the aim of …

Treatment choices and neuropsychological symptoms of a large cohort of early MS

O von Bismarck, T Dankowski… - Neurology …, 2018 - AAN Enterprises
Objective To assess clinical characteristics, distribution of disease-modifying treatments
(DMTs), and neuropsychological symptoms in a large cohort of patients with early-stage MS …

The contribution of illness beliefs, co** strategies, and social support to perceived physical health and fatigue in multiple sclerosis

M Bassi, M Grobberio, L Negri, S Cilia… - Journal of clinical …, 2021 - Springer
This study investigated the relationship of illness beliefs with perceived physical health and
fatigue among persons with multiple sclerosis. Besides direct effects between illness beliefs …